Literature DB >> 16627063

Indications for operative intervention in patients with asymptomatic primary hyperparathyroidism: practice patterns of endocrine surgery.

Maria A Kouvaraki1, Marilyn Greer, Sheena Sharma, David Beery, Robert Armand, Jeffrey E Lee, Douglas B Evans, Nancy D Perrier.   

Abstract

BACKGROUND: Currently, many patients with primary hyperparathyroidism (PHPT) are diagnosed when they are considered to be "asymptomatic." The need for parathyroidectomy in these patients has been questioned. A consensus statement drafted after the National Institutes of Health (NIH) 2002 Workshop on Asymptomatic PHPT provided guidelines for management of such patients but has been criticized for being too conservative. The purpose of this survey was to determine the impact of these guidelines on practice patterns of endocrine surgeons.
METHODS: Members of the American Association of Endocrine Surgeons (AAES) were surveyed to determine whether previously published consensus guidelines for management of asymptomatic patients with PHPT are used to base the decision of whether to offer parathyroidectomy and to ascertain what parameters are considered indicators to proceed with operative intervention. AAES members were asked about the management of patients with asymptomatic PHPT, specialty characteristics, and demographics.
RESULTS: Of 257 AAES members, 96 (37%) responded to the survey. Although the majority of the respondents were aware of and followed the NIH consensus conference guidelines, the majority of surgeons (80%) would operate on a patient with PHPT who did not meet these criteria but had other nonspecific symptoms. Surgeons favored operative intervention when preoperative localization studies were positive, even if the criteria of the NIH guidelines were not fulfilled. Most of the responders who would operate on all patients with PHPT, regardless of objective parameters, were surgeons with a high-volume practice (>30 parathyroidectomies per year). The presence of multiple endocrine neoplasia (MEN) syndromes did not alter the decision to operate on asymptomatic patients.
CONCLUSIONS: Endocrine surgeons do not base the decision to intervene operatively in patients with PHPT solely on objective criteria. Most high-volume, experienced endocrine surgeons believe that subjective complaints warrant operative intervention.

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Year:  2006        PMID: 16627063     DOI: 10.1016/j.surg.2005.09.006

Source DB:  PubMed          Journal:  Surgery        ISSN: 0039-6060            Impact factor:   3.982


  9 in total

1.  Changing biochemical presentation of primary hyperparathyroidism.

Authors:  Martin Almquist; Anders Bergenfelz; Hans Mårtensson; Mark Thier; Erik Nordenström
Journal:  Langenbecks Arch Surg       Date:  2010-07-10       Impact factor: 3.445

2.  Diagnostic value of endoscopic ultrasonography for preoperative localization of parathyroid adenomas.

Authors:  Reyhan Ersoy; Osman Ersoy; Berna Evranos Ogmen; Sefika Burcak Polat; Mehmet Kilic; Nilufer Yildirim; Levent Ozturk; Bekir Cakir
Journal:  Endocrine       Date:  2014-01-11       Impact factor: 3.633

3.  Results from a national survey on the management of primary hyperparathyroidism.

Authors:  M Muñoz Torres; E Jodar Gimeno; R Reyes Garcia; G Martínez Diaz Guerra; J A Amado; S Gaztambide; J M Quesada Gómez
Journal:  J Endocrinol Invest       Date:  2011-12-15       Impact factor: 4.256

Review 4.  Imaging techniques in parathyroid surgery for primary hyperparathyroidism.

Authors:  Arash Mohebati; Ashok R Shaha
Journal:  Am J Otolaryngol       Date:  2011-12-07       Impact factor: 1.808

5.  Localization of Ectopic Mediastinal Parathyroid Adenomas Using Indigo Carmine Injection for Surgical Management: A Preliminary Report.

Authors:  Makoto Kammori; Shinsaku Kanazawa; Hisae Ogata; Natsuki Kanda; Takashi Nagashima; Mahiro Kammori; Toshihisa Ogawa
Journal:  Front Surg       Date:  2022-05-12

6.  Appropriate surgical treatment of lithium-associated hyperparathyroidism.

Authors:  Evie Carchman; Jennifer Ogilvie; Jennifer Holst; John Yim; Sally Carty
Journal:  World J Surg       Date:  2008-10       Impact factor: 3.352

7.  The value of intraoperative parathyroid hormone assay in the surgery of mediastinal ectopic parathyroid adenoma (A case series).

Authors:  Sani Rabiou; Sani M Aminou; Boubacar Efared; Hicham Harmouchi; Marwane Lakranbi; Mounia Serraj; Yassine Ouadnouni; Mohamed Smahi
Journal:  Ann Med Surg (Lond)       Date:  2019-06-27

8.  Undertreatment of primary hyperparathyroidism in a privately insured US population: Decreasing utilization of parathyroidectomy despite expanding surgical guidelines.

Authors:  Carolyn D Seib; Tong Meng; Insoo Suh; Robin M Cisco; Dana T Lin; Arden M Morris; Amber W Trickey; Electron Kebebew
Journal:  Surgery       Date:  2020-07-09       Impact factor: 3.982

9.  Intraoperative Decision-Making and Technical Aspects of Parathyroidectomy in Young Patients With MEN1 Related Hyperparathyroidism.

Authors:  Priscilla F Nobecourt; Jonathan Zagzag; Elliot A Asare; Nancy D Perrier
Journal:  Front Endocrinol (Lausanne)       Date:  2018-10-16       Impact factor: 5.555

  9 in total

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