Literature DB >> 16623669

Gabapentin-induced coma in a patient with renal failure.

Ayhan Dogukan1, Bilge Aygen, Muhammed S Berilgen, Sait Dag, Sevim Bektas, Ali I Gunal.   

Abstract

We describe a 60-year-old woman who became comatose after a single dose of gabapentin for right-sided sciatalgia. The patient was improved by hemodialysis. Gabapentin toxicity should be considered when mental status changes develop in patients with renal failure after even a single dose.

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Year:  2006        PMID： 16623669     DOI： 10.1111/j.1542-4758.2006.00089.x

Source DB:  PubMed          Journal:  Hemodial Int        ISSN： 1492-7535            Impact factor:   1.812


  8 in total

Review 1.  Use of gabapentin in the treatment of behavioural and psychological symptoms of dementia: a review of the evidence.

Authors:  Yunie Kim; Kirsten M Wilkins; Rajesh R Tampi
Journal:  Drugs Aging       Date:  2008       Impact factor: 3.923

2.  71-year-old man with chronic kidney failure and sudden change of mental status.

Authors:  Aaron S Mansfield; Qi Qian
Journal:  Mayo Clin Proc       Date:  2009-11       Impact factor: 7.616

3.  Flumazenil therapy for a gabapentin-induced coma: a case report.

Authors:  M Masciullo; F Pichiorri; G Scivoletto; C Foti; M Molinari
Journal:  J Med Case Rep       Date:  2021-05-09

4.  Treatment of gabapentin-induced myoclonus with continuous renal replacement therapy.

Authors:  A K Guddati; Z Zafar; J T Cheng; S Mohan
Journal:  Indian J Nephrol       Date:  2012-01

Review 5.  Postoperative pain management in patients with chronic kidney disease.

Authors:  Qutaiba A Tawfic; Geoff Bellingham
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2015 Jan-Mar

6.  Gabapentin dose and the 30-day risk of altered mental status in older adults: A retrospective population-based study.

Authors:  Jamie L Fleet; Stephanie N Dixon; Paul John Kuwornu; Varun K Dev; Manuel Montero-Odasso; Jorge Burneo; Amit X Garg
Journal:  PLoS One       Date:  2018-03-14       Impact factor: 3.240

7.  Gabapentin-induced coma: A MR-spectrometry analysis.

Authors:  Lamine Abdennour; Paola Sanchez-Peña; Damien Galanaud; Vincent Navarro; Nicolas Weiss; Louis Puybasset
Journal:  Neuropsychiatr Dis Treat       Date:  2007       Impact factor: 2.570

8.  Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain.

Authors:  Ming-Ming Zhang; Shui-Bing Liu; Tao Chen; Kohei Koga; Ting Zhang; Yun-Qing Li; Min Zhuo
Journal:  Mol Brain       Date:  2014-06-16       Impact factor: 4.041
  8 in total

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