Literature DB >> 16623579

Hybridization of pyrrolidinyl peptide nucleic acids and DNA: selectivity, base-pairing specificity, and direction of binding.

Tirayut Vilaivan1, Choladda Srisuwannaket.   

Abstract

[structure: see text] A mixed-base, beta-amino acid containing, pyrrolidinyl peptide nucleic acid (PNA) binds strongly and selectively to complementary DNA in an exclusively antiparallel fashion. The PNA-DNA binding specificity strictly follows the Watson-Crick base-pairing rules.

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Year:  2006        PMID： 16623579     DOI： 10.1021/ol060448q

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

1.  Pyrrolidinyl peptide nucleic acid with α/β-peptide backbone: A conformationally constrained PNA with unusual hybridization properties.

Authors:  Chotima Vilaivan; Choladda Srisuwannaket; Cheeraporn Ananthanawat; Chaturong Suparpprom; Junji Kawakami; Yoshie Yamaguchi; Yuko Tanaka; Tirayut Vilaivan
Journal:  Artif DNA PNA XNA       Date:  2011-04

Review 2.  Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications.

Authors:  Chaturong Suparpprom; Tirayut Vilaivan
Journal:  RSC Chem Biol       Date:  2022-03-18

3.  Visual genotyping of thalassemia by using pyrrolidinyl peptide nucleic acid probes immobilized on carboxymethylcellulose-modified paper and enzyme-induced pigmentation.

Authors:  Nuttapon Jirakittiwut; Thongperm Munkongdee; Kanet Wongravee; Orapan Sripichai; Suthat Fucharoen; Thanit Praneenararat; Tirayut Vilaivan
Journal:  Mikrochim Acta       Date:  2020-03-18       Impact factor: 5.833

4.  Multiplex Paper-Based Colorimetric DNA Sensor Using Pyrrolidinyl Peptide Nucleic Acid-Induced AgNPs Aggregation for Detecting MERS-CoV, MTB, and HPV Oligonucleotides.

Authors:  Prinjaporn Teengam; Weena Siangproh; Adisorn Tuantranont; Tirayut Vilaivan; Orawon Chailapakul; Charles S Henry
Journal:  Anal Chem       Date:  2017-04-27       Impact factor: 6.986

5.  Conformational Control of Dual Emission by Pyrrolidinyl PNA-DNA Hybrids.

Authors:  Sabrina Sezi; Reji Varghese; Tirayut Vilaivan; Hans-Achim Wagenknecht
Journal:  ChemistryOpen       Date:  2012-07-11       Impact factor: 2.911

6.  Synthesis and optical properties of pyrrolidinyl peptide nucleic acid carrying a clicked Nile red label.

Authors:  Nattawut Yotapan; Chayan Charoenpakdee; Pawinee Wathanathavorn; Boonsong Ditmangklo; Hans-Achim Wagenknecht; Tirayut Vilaivan
Journal:  Beilstein J Org Chem       Date:  2014-09-11       Impact factor: 2.883
  6 in total

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