Literature DB >> 16623549

Construction of beta-haloenamides via direct copper-promoted coupling of lactams with 2-chloro and 2-bromo vinyliodides.

Cuixiang Sun1, Jason E Camp, Steven M Weinreb.   

Abstract

[reaction: see text] Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding beta-haloenamides in moderate to excellent yields.

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Year:  2006        PMID: 16623549     DOI: 10.1021/ol060093a

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  5 in total

1.  Regio- and Stereoselective Synthesis of 1,2-Dihaloalkenes Using In-Situ-Generated ICl, IBr, BrCl, I2, and Br2.

Authors:  Xiaojun Zeng; Shiwen Liu; Yuhao Yang; Yi Yang; Gerald B Hammond; Bo Xu
Journal:  Chem       Date:  2020-04-09       Impact factor: 22.804

2.  Studies towards the synthesis of the marine alkaloid chartelline C.

Authors:  Phillip J Black; Evan A Hecker; Philip Magnus
Journal:  Tetrahedron Lett       Date:  2007-09-03       Impact factor: 2.415

3.  Chemoselectivity: the mother of invention in total synthesis.

Authors:  Ryan A Shenvi; Daniel P O'Malley; Phil S Baran
Journal:  Acc Chem Res       Date:  2009-04-21       Impact factor: 22.384

4.  Metal-free, Regio-, and Stereo-Controlled Hydrochlorination and Hydrobromination of Ynones and Ynamides.

Authors:  Xiaojun Zeng; Zhichao Lu; Shiwen Liu; Gerald B Hammond; Bo Xu
Journal:  J Org Chem       Date:  2017-12-07       Impact factor: 4.354

5.  Hydrogen-Bonding-Assisted Brønsted Acid and Gold Catalysis: Access to Both (E)- and (Z)-1,2-Haloalkenes via Hydrochlorination of Haloalkynes.

Authors:  Xiaojun Zeng; Shiwen Liu; Gerald B Hammond; Bo Xu
Journal:  ACS Catal       Date:  2017-12-15       Impact factor: 13.084

  5 in total

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