Literature DB >> 16622649

Long-term, tunneled, noncuffed central venous catheter in cancer patients (Vygon): safety, efficacy, and complications.

Giovanna Masci1, Massimo Magagnoli, Vittorio Pedicini, Dario Poretti, Luca Castagna, Carlo Carnaghi, Emanuela Morenghi, Antonietta Del Vecchio, Rita Finotto, Giorgio Brambilla, Armando Santoro.   

Abstract

BACKGROUND: Totally implantable or partially cuffed central venous catheters (CVC) are commonly used in cancer patients, but they are often expensive and may produce complications. To minimize costs, we have been using a low-cost, partially tunneled, silicone elastomer catheter with no Dacron cuff or antireflux valve (Vygon) since 2001. This study is a retrospective investigation of our experience using the Vygon catheter as a long-term CVC in patients with malignancy.
MATERIALS AND METHODS: A total of 458 Vygon catheters (Nutricath, Vygon) were percutaneously inserted by an interventional radiologist in 302 cancer patients. The median duration of catheter use was 93 days, mean 164.3 days (range 1-789). Main patient characteristics were as follows: number of male/female patients, 166/136; median age, 51 years; hematological/nonhematological patients, 189/113.
RESULTS: Early complications were pneumothorax in six and hematoma in twelve of 458 implants, respectively. Thirteen out of 302 patients developed a catheter-related thrombosis. One hundred and thirty-five of 458 Vygon catheters required removal because of catheter-related complications: 68 accidental losses, 37 cases of febrile neutropenia suspected to be catheter-related, ten catheter dislodgements, ten catheter malfunctions, four local infections, three thromboses, two catheter ruptures, and one allergic reaction.
CONCLUSION: Vygon catheters do not seem to induce more early and late complications as compared with other more expensive devices, except for disadvantage of the high incidence rate of accidental losses.

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Year:  2006        PMID: 16622649     DOI: 10.1007/s00520-006-0065-2

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  20 in total

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Authors:  L A Mermel; B M Farr; R J Sherertz; I I Raad; N O'Grady; J S Harris; D E Craven
Journal:  Clin Infect Dis       Date:  2001-04-03       Impact factor: 9.079

2.  A novel, simple way to insert percutaneous central venous catheters in newborn babies.

Authors:  Donna Gandini; T H H G Koh
Journal:  J Perinatol       Date:  2003-03       Impact factor: 2.521

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Journal:  Surg Gynecol Obstet       Date:  1992-05

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Journal:  Mayo Clin Proc       Date:  1997-03       Impact factor: 7.616

Review 5.  Venous thromboembolism associated with long-term use of central venous catheters in cancer patients.

Authors:  Melina Verso; Giancarlo Agnelli
Journal:  J Clin Oncol       Date:  2003-10-01       Impact factor: 44.544

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Journal:  N Engl J Med       Date:  1977-06-09       Impact factor: 91.245

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Journal:  Gynecol Oncol       Date:  1989-06       Impact factor: 5.482

8.  An evaluation of Groshong central venous catheters on a gynecologic oncology service.

Authors:  R W Holloway; J W Orr
Journal:  Gynecol Oncol       Date:  1995-02       Impact factor: 5.482

9.  Experience with the Groshong long-term central venous catheter.

Authors:  J E Delmore; D V Horbelt; B L Jack; D K Roberts
Journal:  Gynecol Oncol       Date:  1989-08       Impact factor: 5.482

10.  Nosocomial septicemia in the cancer patient: the influence of central venous access devices, neutropenia, and type of malignancy.

Authors:  V A Morrison; B A Peterson; C D Bloomfield
Journal:  Med Pediatr Oncol       Date:  1990
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  1 in total

1.  Infective and thrombotic complications of central venous catheters in patients with hematological malignancy: prospective evaluation of nontunneled devices.

Authors:  Leon J Worth; John F Seymour; Monica A Slavin
Journal:  Support Care Cancer       Date:  2008-12-19       Impact factor: 3.603

  1 in total

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