| Literature DB >> 16621536 |
Hongxia Sun1, Yalin Tang, Junfeng Xiang, Guangzhi Xu, Yazhou Zhang, Hong Zhang, Lianghua Xu.
Abstract
Quercetin is a kind of flavonoid which has been proved to exhibit anti-tumor activity. The interaction modes of quercetins with monomeric and dimeric G-quadruplexes were studied by absorption, fluorescence, CD, and (1)H NMR spectroscopies. The ligands were found to be stacked with terminal tetrads of monomeric G-quadruplexes by intercalation and bound to dimeric G-quadruplexes by groove binding.Entities:
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Year: 2006 PMID： 16621536 DOI： 10.1016/j.bmcl.2006.03.087
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823