Literature DB >> 16621498

The road much traveled: trafficking in the cell nucleus.

Stanislaw A Gorski1, Miroslav Dundr, Tom Misteli.   

Abstract

Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nucleus and have uncovered some of the structural properties of the nuclear microenvironment. Control of RNA and protein trafficking is now emerging as a physiological regulatory mechanism in gene expression and nuclear function.

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Year:  2006        PMID: 16621498     DOI: 10.1016/j.ceb.2006.03.002

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  46 in total

1.  Changes in chromatin compaction during the cell cycle revealed by micrometer-scale measurement of molecular flow in the nucleus.

Authors:  Elizabeth Hinde; Francesco Cardarelli; Michelle A Digman; Enrico Gratton
Journal:  Biophys J       Date:  2012-02-07       Impact factor: 4.033

2.  In vivo pair correlation analysis of EGFP intranuclear diffusion reveals DNA-dependent molecular flow.

Authors:  Elizabeth Hinde; Francesco Cardarelli; Michelle A Digman; Enrico Gratton
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-07       Impact factor: 11.205

3.  Nucleocytoplasmic distribution is required for activation of resistance by the potato NB-LRR receptor Rx1 and is balanced by its functional domains.

Authors:  Erik Slootweg; Jan Roosien; Laurentiu N Spiridon; Andrei-Jose Petrescu; Wladimir Tameling; Matthieu Joosten; Rikus Pomp; Casper van Schaik; Robert Dees; Jan Willem Borst; Geert Smant; Arjen Schots; Jaap Bakker; Aska Goverse
Journal:  Plant Cell       Date:  2010-12-21       Impact factor: 11.277

4.  Arabidopsis chromatin-associated HMGA and HMGB use different nuclear targeting signals and display highly dynamic localization within the nucleus.

Authors:  Dorte Launholt; Thomas Merkle; Andreas Houben; Alexander Schulz; Klaus D Grasser
Journal:  Plant Cell       Date:  2006-11-17       Impact factor: 11.277

5.  Intranuclear binding kinetics and mobility of single native U1 snRNP particles in living cells.

Authors:  David Grünwald; Beatrice Spottke; Volker Buschmann; Ulrich Kubitscheck
Journal:  Mol Biol Cell       Date:  2006-09-20       Impact factor: 4.138

6.  Internal dynamics of a living cell nucleus investigated by dynamic light scattering.

Authors:  M Suissa; C Place; E Goillot; E Freyssingeas
Journal:  Eur Phys J E Soft Matter       Date:  2008-08       Impact factor: 1.890

7.  The mean frequency of transcriptional bursting and its variation in single cells.

Authors:  Moxun Tang
Journal:  J Math Biol       Date:  2009-03-10       Impact factor: 2.259

8.  Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair.

Authors:  Jason Gorman; Feng Wang; Sy Redding; Aaron J Plys; Teresa Fazio; Shalom Wind; Eric E Alani; Eric C Greene
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-24       Impact factor: 11.205

9.  Recombination-induced tag exchange to track old and new proteins.

Authors:  Kitty F Verzijlbergen; Victoria Menendez-Benito; Tibor van Welsem; Sjoerd J van Deventer; Derek L Lindstrom; Huib Ovaa; Jacques Neefjes; Daniel E Gottschling; Fred van Leeuwen
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-14       Impact factor: 11.205

10.  Aberrant mRNA transcripts and the nonsense-mediated decay proteins UPF2 and UPF3 are enriched in the Arabidopsis nucleolus.

Authors:  Sang Hyon Kim; Olga A Koroleva; Dominika Lewandowska; Ali F Pendle; Gillian P Clark; Craig G Simpson; Peter J Shaw; John W S Brown
Journal:  Plant Cell       Date:  2009-07-14       Impact factor: 11.277

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