Literature DB >> 1662025

Hygromycin B therapy of a murine coronaviral hepatitis.

G Macintyre1, B Curry, F Wong, R Anderson.   

Abstract

Hepatitis caused by mouse hepatitis virus (MHV-A59), a murine coronavirus, is accompanied by direct infection and replication of virus within the liver. We demonstrate here that the aminoglycoside hygromycin B is able to eliminate MHV-A59 infection from mouse peritoneal macrophages and cultured liver cells in vitro and is also able to reduce levels of virus replication and necrotic liver foci in vivo.

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Year:  1991        PMID： 1662025      PMCID： PMC245338          DOI： 10.1128/AAC.35.10.2125

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

1.  Increased sensitivity of virus-infected cells to inhibitors of protein synthesis does not correlate with changes in plasma membrane permeability.

Authors:  J M Cameron; M J Clemens; M A Gray; D E Menzies; B J Mills; A P Warren; C A Pasternak
Journal:  Virology       Date:  1986-12       Impact factor: 3.616

2.  Neutral-red uptake and expression of monocytic antigens in amniotic-fluid mononuclear phagocytes: evaluation of a novel approach for prenatal diagnosis of neural-tube defects.

Authors:  K Polgár; G Abel; S Sipka; Z Papp
Journal:  Am J Reprod Immunol Microbiol       Date:  1988-11

3.  Neutral-red uptake by amniotic-fluid macrophages in neural-tube defects: a rapid test.

Authors:  K Polgár; S Sipka; G Abel; Z Papp
Journal:  N Engl J Med       Date:  1984-05-31       Impact factor: 91.245

4.  Inhibition of animal virus production by means of translation inhibitors unable to penetrate normal cells.

Authors:  A Benedetto; G B Rossi; C Amici; F Belardelli; L Cioè; G Carruba; L Carrasco
Journal:  Virology       Date:  1980-10-15       Impact factor: 3.616

5.  Control of mouse hepatitis virus replication in macrophages by a recessive gene on chromosome 7.

Authors:  M S Smith; R E Click; P G Plagemann
Journal:  J Immunol       Date:  1984-07       Impact factor: 5.422

Review 6.  Molecular biology of animal virus infection.

Authors:  L Carrasco; A E Smith
Journal:  Pharmacol Ther       Date:  1980       Impact factor: 12.310

7.  Translational regulation in mouse hepatitis virus infection is not mediated by altered intracellular ion concentrations.

Authors:  L Mizzen; G Macintyre; F Wong; R Anderson
Journal:  J Gen Virol       Date:  1987-08       Impact factor: 3.891

8.  A model for persistent murine coronavirus infection involving maintenance via cytopathically infected cell centres.

Authors:  G Macintyre; F Wong; R Anderson
Journal:  J Gen Virol       Date:  1989-03       Impact factor: 3.891

9.  Intracellular accumulation of a fluorescent derivative of paromomycin in human fibroblasts.

Authors:  J H Buchanan; S I Rattan; A Stevens; R Holliday
Journal:  J Cell Biochem       Date:  1982       Impact factor: 4.429

10.  Augmentation of organ-associated natural killer activity by biological response modifiers. Isolation and characterization of large granular lymphocytes from the liver.

Authors:  R H Wiltrout; B J Mathieson; J E Talmadge; C W Reynolds; S R Zhang; R B Herberman; J R Ortaldo
Journal:  J Exp Med       Date:  1984-11-01       Impact factor: 14.307
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  7 in total

1.  Hygromycin B inhibits synthesis of murine coronavirus RNA.

Authors:  G Macintyre; D E Woods; R Anderson
Journal:  Antimicrob Agents Chemother       Date:  1991-12       Impact factor: 5.191

2.  Hygromycin B resistance mediates elimination of Leishmania virus from persistently infected parasites.

Authors:  Y T Ro; S M Scheffter; J L Patterson
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

3.  Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth.

Authors:  Benjamin W Neuman; David A Stein; Andrew D Kroeker; Amy D Paulino; Hong M Moulton; Patrick L Iversen; Michael J Buchmeier
Journal:  J Virol       Date:  2004-06       Impact factor: 5.103

4.  Antiviral activity of geneticin against dengue virus.

Authors:  Xianchao G Zhang; Peter W Mason; Edward J Dubovi; Xiaodong Xu; Nigel Bourne; Randall W Renshaw; Timothy M Block; Alexander V Birk
Journal:  Antiviral Res       Date:  2009-03-11       Impact factor: 5.970

5.  Aminoglycosides and their potential as SARS-CoV-2 antivirals.

Authors:  Nevio Cimolai
Journal:  Med Hypotheses       Date:  2021-03-23       Impact factor: 1.538

Review 6.  Animal and human RNA viruses: genetic variability and ability to overcome vaccines.

Authors:  T G Villa; Ana G Abril; S Sánchez; T de Miguel; A Sánchez-Pérez
Journal:  Arch Microbiol       Date:  2020-09-28       Impact factor: 2.552

Review 7.  Feline Coronavirus Antivirals: A Review.

Authors:  Manon Delaplace; Hélène Huet; Adèle Gambino; Sophie Le Poder
Journal:  Pathogens       Date:  2021-09-07
  7 in total

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