Literature DB >> 16619016

The integration of cell and chemical biology in protein folding.

Jeffery W Kelly1, William E Balch.   

Abstract

Eukaryotic cells are specialized, interdependent functional units of complex tissues that are composed of metabolically integrated systems defined by chemically distinct organelles that operate as reaction vessels. It is now clear that the small-molecule and polymer-based composition of these organelles plays a crucial role in generating and maintaining protein folds and functions through the systems chemistry of the local environments.

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Year:  2006        PMID： 16619016     DOI： 10.1038/nchembio0506-224

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


  11 in total

1.  Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements.

Authors:  Graham M West; Chandra L Tucker; Tao Xu; Sung Kyu Park; Xuemei Han; John R Yates; Michael C Fitzgerald
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-03       Impact factor: 11.205

Review 2.  Protein energetics in maturation of the early secretory pathway.

Authors:  R Luke Wiseman; Atanas Koulov; Evan Powers; Jeffery W Kelly; William E Balch
Journal:  Curr Opin Cell Biol       Date:  2007-08-07       Impact factor: 8.382

3.  Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis.

Authors:  Francis J Roushar; Timothy C Gruenhagen; Wesley D Penn; Bian Li; Jens Meiler; Beata Jastrzebska; Jonathan P Schlebach
Journal:  J Am Chem Soc       Date:  2018-12-26       Impact factor: 15.419

4.  Homeostatic adaptations in brain energy metabolism in mouse models of Huntington disease.

Authors:  Ivan Tkac; Pierre-Gilles Henry; Lori Zacharoff; Michael Wedel; Wuming Gong; Dinesh K Deelchand; Tongbin Li; Janet M Dubinsky
Journal:  J Cereb Blood Flow Metab       Date:  2012-07-18       Impact factor: 6.200

Review 5.  Controlling subcellular delivery to optimize therapeutic effect.

Authors:  Mohanad Mossalam; Andrew S Dixon; Carol S Lim
Journal:  Ther Deliv       Date:  2010-07

6.  The safety dance: biophysics of membrane protein folding and misfolding in a cellular context.

Authors:  Jonathan P Schlebach; Charles R Sanders
Journal:  Q Rev Biophys       Date:  2014-11-25       Impact factor: 5.318

7.  ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells.

Authors:  Laurence Suaud; Katelyn Miller; Lora Alvey; Wusheng Yan; Amal Robay; Catherine Kebler; James L Kreindler; Susan Guttentag; Michael J Hubbard; Ronald C Rubenstein
Journal:  J Biol Chem       Date:  2011-04-27       Impact factor: 5.157

8.  Chemical and biological folding contribute to temperature-sensitive DeltaF508 CFTR trafficking.

Authors:  Xiaodong Wang; Atanas V Koulov; Wendy A Kellner; John R Riordan; William E Balch
Journal:  Traffic       Date:  2008-07-30       Impact factor: 6.215

9.  Pharmacological chaperoning: two 'hits' are better than one.

Authors:  William R Skach
Journal:  Biochem J       Date:  2007-09-01       Impact factor: 3.857

10.  Influence of Pathogenic Mutations on the Energetics of Translocon-Mediated Bilayer Integration of Transmembrane Helices.

Authors:  Jonathan P Schlebach; Charles R Sanders
Journal:  J Membr Biol       Date:  2014-09-06       Impact factor: 1.843
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