| Literature DB >> 16619013 |
Abstract
Both biochemical and live cell imaging studies suggest the existence of lipid rafts, specialized membrane microdomains that promote interaction among signaling molecules. Although their composition is still poorly understood, these highly dynamic domains are enriched in cholesterol, sphingolipids, and particular groups of proteins. The mechanism(s) by which trafficking into or out of lipid rafts affects signaling remains unclear.Entities:
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Year: 2006 PMID: 16619013 DOI: 10.1038/sj.jid.5700282
Source DB: PubMed Journal: J Invest Dermatol ISSN: 0022-202X Impact factor: 8.551