Literature DB >> 1661828

Regulation of NGF gene expression in CNS glia by cell-cell contact.

B Lu1, J M Lee, R Elliott, C F Dreyfus, J E Adler, I B Black.   

Abstract

Nerve growth factor (NGF) gene expression in central nervous system (CNS) glia appears to be associated with active glial growth. To study the underlying molecular mechanisms, we examined the effects of a number of growth-related factors on NGF mRNA expression in glial cultures. Our results suggest that glial membrane interaction, as a consequence of growth, actively inhibits NGF gene expression in CNS glia.

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Year:  1991        PMID: 1661828     DOI: 10.1016/0169-328x(91)90046-z

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN: 0169-328X


  2 in total

1.  A time-dependent increase in glial fibrillary acidic protein expression and glutamine synthetase activity in long-term subculture of the GL15 glioma cell line.

Authors:  G Moretto; N Brutti; V De Angelis; C Arcuri; V Bocchini
Journal:  Cell Mol Neurobiol       Date:  1997-10       Impact factor: 5.046

2.  Interleukin-1beta and anaphylatoxins exert a synergistic effect on NGF expression by astrocytes.

Authors:  Anne-christine Jauneau; Alexander Ischenko; Alexandra Chatagner; Magalie Benard; Philippe Chan; Marie-therese Schouft; Christine Patte; Hubert Vaudry; Marc Fontaine
Journal:  J Neuroinflammation       Date:  2006-04-04       Impact factor: 8.322

  2 in total

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