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Literature DB >> 1661704

Human NK-2 receptor gene maps to chromosome region 10q11-21.

J E Morten¹, B Hopkins, S J Powell, A Graham.

Abstract

The human NK-2 receptor gene has been mapped to chromosome 10 using the polymerase chain reaction to amplify specifically the human NK-2 receptor sequence in hamster/human hybrid DNA and also in mouse/human monochromosome hybrids. The assignment to chromosome 10 was confirmed by in situ hybridisation to human metaphase chromosomes, giving a regional localisation of 10q11-21.

Entities: Gene Species

Mesh：

Substances：

Year: 1991 PMID： 1661704 DOI： 10.1007/bf00206072

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

16 in total

1. Cloning and expression of a rat neuromedin K receptor cDNA.

Authors: R Shigemoto; Y Yokota; K Tsuchida; S Nakanishi
Journal: J Biol Chem Date: 1990-01-15 Impact factor: 5.157

2. Molecular characterization of a functional cDNA encoding the rat substance P receptor.

Authors: A D Hershey; J E Krause
Journal: Science Date: 1990-02-23 Impact factor: 47.728

3. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.

Authors: R K Saiki; S Scharf; F Faloona; K B Mullis; G T Horn; H A Erlich; N Arnheim
Journal: Science Date: 1985-12-20 Impact factor: 47.728

4. Molecular characterization of rat substance K receptor and its mRNAs.

Authors: Y Sasai; S Nakanishi
Journal: Biochem Biophys Res Commun Date: 1989-12-15 Impact factor: 3.575

5. Molecular characterization of a functional cDNA for rat substance P receptor.

Authors: Y Yokota; Y Sasai; K Tanaka; T Fujiwara; K Tsuchida; R Shigemoto; A Kakizuka; H Ohkubo; S Nakanishi
Journal: J Biol Chem Date: 1989-10-25 Impact factor: 5.157

6. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues.

Authors: N P Gerard; R L Eddy; T B Shows; C Gerard
Journal: J Biol Chem Date: 1990-11-25 Impact factor: 5.157

Human NK-2 receptor gene maps to chromosome region 10q11-21.

1. Cloning and expression of a rat neuromedin K receptor cDNA.

2. Molecular characterization of a functional cDNA encoding the rat substance P receptor.

3. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.

4. Molecular characterization of rat substance K receptor and its mRNAs.

5. Molecular characterization of a functional cDNA for rat substance P receptor.

6. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues.

7. Isolation and characterisation of the human lung NK-2 receptor gene using rapid amplification of cDNA ends.

8. The G-banded prophase chromosomes of man.

9. Genetic manipulation by means of microcell-mediated transfer of normal human chromosomes into recipient mouse cells.

10. Substance K: a novel mammalian tachykinin that differs from substance P in its pharmacological profile.

1. A multiple interval physical map of the pericentromeric region of human chromosome 10.