Literature DB >> 16615901

A monotopic membrane protein goes solo.

Andrea Mattevi.   

Abstract

Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.

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Year:  2006        PMID: 16615901     DOI: 10.1016/j.str.2006.03.002

Source DB:  PubMed          Journal:  Structure        ISSN: 0969-2126            Impact factor:   5.006


  3 in total

1.  Diacyltransferase Activity and Chain Length Specificity of Mycobacterium tuberculosis PapA5 in the Synthesis of Alkyl β-Diol Lipids.

Authors:  Megan H Touchette; Gopal R Bommineni; Richard J Delle Bovi; John E Gadbery; Carrie D Nicora; Anil K Shukla; Jennifer E Kyle; Thomas O Metz; Dwight W Martin; Nicole S Sampson; W Todd Miller; Peter J Tonge; Jessica C Seeliger
Journal:  Biochemistry       Date:  2015-08-24       Impact factor: 3.162

2.  Role of the amphipathic peptide of Semliki forest virus replicase protein nsP1 in membrane association and virus replication.

Authors:  Pirjo Spuul; Anne Salonen; Andres Merits; Eija Jokitalo; Leevi Kääriäinen; Tero Ahola
Journal:  J Virol       Date:  2006-11-08       Impact factor: 5.103

Review 3.  Monotopic Membrane Proteins Join the Fold.

Authors:  Karen N Allen; Sonya Entova; Leah C Ray; Barbara Imperiali
Journal:  Trends Biochem Sci       Date:  2018-10-15       Impact factor: 13.807

  3 in total

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