Bin Zhang1, Zhen-Gang Xu, Ping-Zhang Tang. 1. Department of Head and Neck Surgery Cancer Hospital (Institute), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, PR China. docbinzhang@hotmail.com
Abstract
BACKGROUND: Despite the introduction of modern imaging techniques, it is still difficult to detect microscopic disease in neck nodes. The purpose of this study is to evaluate the efficacy of the lateral neck dissection (LND) for elective treatment of the clinically node negative neck (cN0) in laryngeal squamous cell carcinoma (SCC). METHODS: The clinical records of 110 cN0 patients with laryngeal SCC treated in this hospital from January 1997 to December 2002 were reviewed retrospectively. RESULTS: One hundred ten patients received 145 elective LND. Occult metastasis was detected in 22 (20.0%) of this group of patients. The distribution of the 37 positive nodes was as follows: Level II 56.8%; Level III 37.8%; Level IV 5.4%. The 3-year neck recurrence rate estimated by the Kaplan-Meier approach for all cN0 patients (n = 110) was 5.4% [95% CI: 0.0%; 12.5%]. No significant difference in 3-year lymph node recurrence was found between node negative and node positive groups, between supraglottis and glottis groups, or between surgery alone and combined therapy groups. CONCLUSION: The lateral neck dissection is effective in elective treatment of the neck in patients with laryngeal carcinoma. Copyright 2006 Wiley-Liss, Inc.
BACKGROUND: Despite the introduction of modern imaging techniques, it is still difficult to detect microscopic disease in neck nodes. The purpose of this study is to evaluate the efficacy of the lateral neck dissection (LND) for elective treatment of the clinically node negative neck (cN0) in laryngeal squamous cell carcinoma (SCC). METHODS: The clinical records of 110 cN0 patients with laryngeal SCC treated in this hospital from January 1997 to December 2002 were reviewed retrospectively. RESULTS: One hundred ten patients received 145 elective LND. Occult metastasis was detected in 22 (20.0%) of this group of patients. The distribution of the 37 positive nodes was as follows: Level II 56.8%; Level III 37.8%; Level IV 5.4%. The 3-year neck recurrence rate estimated by the Kaplan-Meier approach for all cN0 patients (n = 110) was 5.4% [95% CI: 0.0%; 12.5%]. No significant difference in 3-year lymph node recurrence was found between node negative and node positive groups, between supraglottis and glottis groups, or between surgery alone and combined therapy groups. CONCLUSION: The lateral neck dissection is effective in elective treatment of the neck in patients with laryngeal carcinoma. Copyright 2006 Wiley-Liss, Inc.
Authors: Soon-Hyun Ahn; Hyun Jun Hong; Soon Young Kwon; Kee Hwan Kwon; Jong-Lyel Roh; Junsun Ryu; Jun Hee Park; Seung-Kuk Baek; Guk Haeng Lee; Sei Young Lee; Jin Choon Lee; Man Ki Chung; Young Hoon Joo; Yong Bae Ji; Jeong Hun Hah; Minsu Kwon; Young Min Park; Chang Myeon Song; Sung-Chan Shin; Chang Hwan Ryu; Doh Young Lee; Young Chan Lee; Jae Won Chang; Ha Min Jeong; Jae-Keun Cho; Wonjae Cha; Byung Joon Chun; Ik Joon Choi; Hyo Geun Choi; Kang Dae Lee Journal: Clin Exp Otorhinolaryngol Date: 2017-01-03 Impact factor: 3.372
Authors: M C Ketterer; L A Lemus Moraga; U Beitinger; J Pfeiffer; A Knopf; C Becker Journal: Eur Arch Otorhinolaryngol Date: 2020-02-11 Impact factor: 2.503
Authors: Giovanni Salzano; Francesco Perri; Fabio Maglitto; Giulia Togo; Gianluca Renato De Fazio; Michela Apolito; Federica Calabria; Claudia Laface; Luigi Angelo Vaira; Umberto Committeri; Mario Balia; Ettore Pavone; Corrado Aversa; Francesco Antonio Salzano; Vincenzo Abbate; Alessandro Ottaiano; Marco Cascella; Mariachiara Santorsola; Roberta Fusco; Luigi Califano; Franco Ionna Journal: J Pers Med Date: 2021-11-25