Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Induction of signet ring cell carcinomas in X-irradiated hypocatalasemic mice (C3H/Cbs).

Literature DB >> 1661279

Induction of signet ring cell carcinomas in X-irradiated hypocatalasemic mice (C3H/Cbs).

H Watanabe¹, P O Ogundigie, T Takahashi, T Ishimoto, A Ito.

Abstract

The stomach region of hypocatalasemic mice of both sexes was X-irradiated once with a dose of 20 Gy. Thirteen months after the irradiation, 3 out of 13 (20%) males and 2 out of 9 (15%) females were observed to have developed signet ring cell carcinomas in the glandular stomach. This finding was statistically significant (P less than 0.01 in males and P less than 0.05 in females) compared to a total absence of similar tumors in the non-irradiated controls. Local invasion of malignant tumors into muscle and subserosal layers was observed, but no metastatic tumors were found in distant organs.

Entities: Chemical Disease Gene Species

Mesh：

Year: 1991 PMID： 1661279 PMCID： PMC5918321 DOI： 10.1111/j.1349-7006.1991.tb01774.x

Source DB: PubMed Journal: Jpn J Cancer Res ISSN： 0910-5050

N‐methyl‐N′‐nitro‐N‐nitrosoguanidine N‐ethyl‐N′‐nitro‐N‐nitrosoguanidine N‐nitrobutylurea periodic acid‐Schiff hypocatalasemic mice

8 in total

1. The effects of pretreatment with stomach extract on the incidence of X-ray-induced gastric tumor in ICR mice.

Authors: H Watanabe; M Naito; K Kawashima; A Ito
Journal: Gan Date: 1984-10

2. Enhancement of gastric carcinogenesis in dogs given N-methyl-N'-nitro-N-nitrosoguanidine following vagotomy.

Authors: M Fujita; M Takami; M Usugane; S Nampei; T Taguchi
Journal: Cancer Res Date: 1979-03 Impact factor: 12.701

3. Effect of gastro-entero-pancreatic endocrine hormones on the histogenesis of gastric cancer in rats induced by N-methyl-N'-nitro-N-nitrosoguanidine; with special reference to development of scirrhous gastric cancer.

Authors: E Tahara; S Haizuka
Journal: Gan Date: 1975-08

4. Acatalasemic and hypocatalasemic mouse mutants.

Authors: R N Feinstein; J B Howard; J T Braun; J E Seaholm
Journal: Genetics Date: 1966-05 Impact factor: 4.562

5. A mode of incipient growth in chemically induced signet ring cell carcinoma of the canine stomach.

Authors: H Watanabe; F Hirose; S Takizawa; Y Terada; I Fujii; T Ohkita
Journal: Pathol Res Pract Date: 1979-01 Impact factor: 3.250

6. Effects in rats of sodium chloride on experimental gastric cancers induced by N-methyl-N-nitro-N-nitrosoguanidine or 4-nitroquinoline-1-oxide.

Authors: M Tatematsu; M Takahashi; S Fukushima; M Hananouchi; T Shirai
Journal: J Natl Cancer Inst Date: 1975-07 Impact factor: 13.506

7. Correlation between induction of duodenal tumor by hydrogen peroxide and catalase activity in mice.

Authors: A Ito; H Watanabe; M Naito; Y Naito; K Kawashima
Journal: Gan Date: 1984-01

8. Duration of ENNG administration and its effect on histological differentiation of experimental gastric cancer.

Authors: M Sunagawa; K Takeshita; A Nakajima; K Ochi; H Habu; M Endo
Journal: Br J Cancer Date: 1985-11 Impact factor: 7.640

8 in total

6 in total

1. Thirty-five-year-old woman with signet ring cell gastric carcinoma secondary to the chernobyl nuclear accident: a case report.

Authors: Kim Mayhall; Masoumeh Ghayouri; Katherine Henry; Veronica Margin; Domeinico Copolla; Rodney Shackelford
Journal: Case Rep Oncol Date: 2013-03-21

2. Signet Ring Cell Gastric Cancer Occurring after Radiation Therapy for Helicobacter pylori-Uninfected Mucosa-Associated Lymphoid Tissue Lymphoma.

Authors: Naoki Asano; Katsunori Iijima; Shiho Terai; Kaname Uno; Hiroyuki Endo; Tomoyuki Koike; Wataru Iwai; Toshimitsu Iwabuchi; Waku Hatta; Yasuhiko Abe; Akira Imatani; Tooru Shimosegawa
Journal: Case Rep Gastroenterol Date: 2011-06-07