Literature DB >> 16612533

Antibiotic use in tonsillectomies: therapeutic or prophylactic? Required or excessive?

Otávio Bejzman Piltcher1, Fabiana Bortoncello Scarton.   

Abstract

Adenotonsillectomy is one of the most commonly performed surgeries in the pediatric and young adult populations. The postoperative morbidity of this surgical procedure is often significant, including odynophagia, dysphagia, fever, halitosis, loss of weight and reduced oral intake. After tonsillectomy, with or without adenoidectomy, the colonization of the open tonsillar fossae by the bacterial population of the oral cavity would cause an exacerbation of the local inflammatory response worsening postoperative pain. The hypothesis that a reduction of the bacterial population of an open surgical wound could minimize the local inflammation, stimulate the healing process and hasten recovery triggered a considerable number of studies addressing the relation between the use of perioperative antibiotics and postoperative morbidity of adenotonsillectomy. In spite of the fact that those studies claim to perform an assessment of the surgical prophylactic use of antibiotics, their outline is not in compliance with the worldwide-accepted principles of surgical antibiotic prophylaxis. By performing a critical review of the literature, the authors discuss the advantages and disadvantages of using antibiotics in tonsillectomies or adenotonsillectomies, as well as the most appropriate definition for its utilization.

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Year:  2006        PMID: 16612533      PMCID: PMC9442137          DOI: 10.1016/s1808-8694(15)31275-1

Source DB:  PubMed          Journal:  Braz J Otorhinolaryngol        ISSN: 1808-8686


  17 in total

1.  Wound infection in otolaryngologic surgery and the inexpediency of antibiotic prophylaxis.

Authors:  M S STRONG
Journal:  Laryngoscope       Date:  1963-02       Impact factor: 3.325

2.  Antibiotic prophylaxis post-tonsillectomy: is it of benefit?

Authors:  M P Colreavy; D Nanan; M Benamer; M Donnelly; A W Blaney; T P O'Dwyer; M Cafferkey
Journal:  Int J Pediatr Otorhinolaryngol       Date:  1999-10-15       Impact factor: 1.675

3.  The effective period of preventive antibiotic action in experimental incisions and dermal lesions.

Authors:  J F Burke
Journal:  Surgery       Date:  1961-07       Impact factor: 3.982

4.  Effect of topical antibiotic therapy on recovery after tonsillectomy in adults.

Authors:  E A Mann; E A Blair; A J Levy; A Chang
Journal:  Otolaryngol Head Neck Surg       Date:  1999-09       Impact factor: 3.497

5.  The efficacy of cefaclor vs amoxicillin on recovery after tonsillectomy in children.

Authors:  J Jones; S D Handler; M Guttenplan; W Potsic; R Wetmore; L W Tom; R Marsh
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1990-05

6.  Postoperative risks of pediatric tonsilloadenoidectomy.

Authors:  J S Carithers; D E Gebhart; J A Williams
Journal:  Laryngoscope       Date:  1987-04       Impact factor: 3.325

7.  The efficacy of perioperative antibiotic therapy on recovery following tonsillectomy in adults: randomized double-blind placebo-controlled trial.

Authors:  J R Grandis; J T Johnson; R M Vickers; V L Yu; M M Wagener; R L Wagner; K A Kachman
Journal:  Otolaryngol Head Neck Surg       Date:  1992-02       Impact factor: 3.497

8.  Post-tonsillectomy hemorrhage: incidence, prevention and management.

Authors:  S D Handler; L Miller; K H Richmond; C C Baranak
Journal:  Laryngoscope       Date:  1986-11       Impact factor: 3.325

9.  An audit of prophylactic antibiotic treatment following tonsillectomy in children.

Authors:  W C Lee; M C Duignan; R M Walsh; J R McRae-Moore
Journal:  J Laryngol Otol       Date:  1996-04       Impact factor: 1.469

10.  Microbiology of the tonsils and adenoids in a pediatric population.

Authors:  R M DeDio; L W Tom; K L McGowan; R F Wetmore; S D Handler; W P Potsic
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1988-07
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  3 in total

Review 1.  Antibiotic prophylaxis in otolaryngologic surgery.

Authors:  Ana Carolina Xavier Ottoline; Shiro Tomita; Marise da Penha Costa Marques; Felippe Felix; Priscila Novaes Ferraiolo; Roberta Silveira Santos Laurindo
Journal:  Int Arch Otorhinolaryngol       Date:  2013-01

2.  Antibiotics for Post-Tonsillectomy Morbidity: Comparative Analysis of a Single Institutional Experience.

Authors:  Qais Aljfout; Amjad Alississ; Hesham Rashdan; Abdullah Maita; Mohammad Saraireh
Journal:  J Clin Med Res       Date:  2016-03-20

3.  Effect of placebo versus prophylactic postoperative amoxicillin on post-(adeno) tonsillectomy morbidity in Tanzanian children: a two-centre, double-blind randomized controlled non-inferiority trial.

Authors:  Denis Katundu; Desderius Chussi; Balthazar Nyombi; Rune Philemon; Hadija Semvua; Gerjon Hannink; Niels van Heerbeek
Journal:  Pan Afr Med J       Date:  2022-06-22
  3 in total

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