Literature DB >> 16612404

The developing role of receptors and adaptors.

Charles Massie1, Ian G Mills.   

Abstract

The response of a cell to the myriad of signals that it receives is varied, and it is dependent on many different factors. The most-studied responses involve growth-factor signalling and these signalling cascades have become key targets for cancer therapy. Recent reports have indicated that growth-factor receptors and associated adaptors can accumulate in the nucleus. Are there novel functions for these proteins that might affect our understanding of their role in cancer and have implications for drug resistance?

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Year:  2006        PMID： 16612404     DOI： 10.1038/nrc1882

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  28 in total

Review 1.  Nuclear trafficking of the epidermal growth factor receptor family membrane proteins.

Authors:  Y-N Wang; H Yamaguchi; J-M Hsu; M-C Hung
Journal:  Oncogene       Date:  2010-05-17       Impact factor: 9.867

2.  Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation.

Authors:  Erine H Budi; Larissa B Patterson; David M Parichy
Journal:  Development       Date:  2008-05-28       Impact factor: 6.868

3.  COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport.

Authors:  Ying-Nai Wang; Hongmei Wang; Hirohito Yamaguchi; Hong-Jen Lee; Heng-Huan Lee; Mien-Chie Hung
Journal:  Biochem Biophys Res Commun       Date:  2010-07-30       Impact factor: 3.575

Review 4.  On mammary gland growth factors: roles in normal development and in cancer.

Authors:  Mien-Chie Hung
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-08-01       Impact factor: 10.005

Review 5.  Spatial regulation of receptor tyrosine kinases in development and cancer.

Authors:  Jessica B Casaletto; Andrea I McClatchey
Journal:  Nat Rev Cancer       Date:  2012-05-24       Impact factor: 60.716

6.  Ultraviolet irradiation can induce evasion of colon cancer cells from stimulation of epidermal growth factor.

Authors:  Seiji Adachi; Ichiro Yasuda; Masanori Nakashima; Takahiro Yamauchi; Junji Kawaguchi; Masahito Shimizu; Masahiko Itani; Momoko Nakamura; Yumi Nishii; Takashi Yoshioka; Yoshinobu Hirose; Yukio Okano; Hisataka Moriwaki; Osamu Kozawa
Journal:  J Biol Chem       Date:  2011-06-06       Impact factor: 5.157

7.  HER family receptor abnormalities in lung cancer brain metastases and corresponding primary tumors.

Authors:  Menghong Sun; Carmen Behrens; Lei Feng; Natalie Ozburn; Ximing Tang; Guosheng Yin; Ritsuko Komaki; Marileila Varella-Garcia; Waun Ki Hong; Kenneth D Aldape; Ignacio I Wistuba
Journal:  Clin Cancer Res       Date:  2009-07-21       Impact factor: 12.531

8.  (-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells.

Authors:  Seiji Adachi; Tomokazu Nagao; Satoshi To; Andrew K Joe; Masahito Shimizu; Rie Matsushima-Nishiwaki; Osamu Kozawa; Hisataka Moriwaki; Frederick R Maxfield; I Bernard Weinstein
Journal:  Carcinogenesis       Date:  2008-06-26       Impact factor: 4.944

9.  c-Met must translocate to the nucleus to initiate calcium signals.

Authors:  Dawidson A Gomes; Michele A Rodrigues; M Fatima Leite; Marcus V Gomez; Peter Varnai; Tamas Balla; Anton M Bennett; Michael H Nathanson
Journal:  J Biol Chem       Date:  2007-12-11       Impact factor: 5.157

10.  Nucleocytoplasmic shuttling of the adapter protein SH2B1beta (SH2-Bbeta) is required for nerve growth factor (NGF)-dependent neurite outgrowth and enhancement of expression of a subset of NGF-responsive genes.

Authors:  Travis J Maures; Linyi Chen; Christin Carter-Su
Journal:  Mol Endocrinol       Date:  2009-04-16
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