Literature DB >> 16611003

Microemulsions: a potential drug delivery system.

P K Ghosh1, R S R Murthy.   

Abstract

Microemulsions are clear, transparent, thermodynamically stable dispersions of oil and water, stabilised by an interfacial film of surfactant frequently in combination with a co-surfactant. Recently, there has been a considerable interest for the microemulsion formulation, for the delivery of hydrophilic as well as lipophilic drug as drug carriers because of its improved drug solubilisation capacity, long shelf life, easy of preparation and improvement of bioavailability. In this present review, we discuss about the various advantages of microemulsion in pharmaceuticals, along with its composition variables, physicochemical characterisation etc. The potential use of microemulsion for therapeutic application is also discussed.

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Year:  2006        PMID: 16611003     DOI: 10.2174/156720106776359168

Source DB:  PubMed          Journal:  Curr Drug Deliv        ISSN: 1567-2018            Impact factor:   2.565


  21 in total

1.  Formulation development and optimization using nanoemulsion technique: a technical note.

Authors:  Sheikh Shafiq-un-Nabi; Faiyaz Shakeel; Sushma Talegaonkar; Javed Ali; Sanjula Baboota; Alka Ahuja; Roop K Khar; Mushir Ali
Journal:  AAPS PharmSciTech       Date:  2007-04-06       Impact factor: 3.246

2.  Enhanced stability of ramipril in nanoemulsion containing cremophor-EL: a technical note.

Authors:  Sheikh Shafiq; Faiyaz Shakeel; Roop K Khar
Journal:  AAPS PharmSciTech       Date:  2008-10-29       Impact factor: 3.246

3.  Oral bioavailability enhancement of exemestane from self-microemulsifying drug delivery system (SMEDDS).

Authors:  Ajeet K Singh; Akash Chaurasiya; Anshumali Awasthi; Gautam Mishra; Dinesh Asati; Roop K Khar; Rama Mukherjee
Journal:  AAPS PharmSciTech       Date:  2009-07-17       Impact factor: 3.246

4.  Factors affecting the stability of nanoemulsions--use of artificial neural networks.

Authors:  Amir Amani; Peter York; Henry Chrystyn; Brian J Clark
Journal:  Pharm Res       Date:  2009-11-12       Impact factor: 4.200

5.  Microemulsion-based antifungal gel delivery to nail for the treatment of onychomycosis: formulation, optimization, and efficacy studies.

Authors:  Bhavesh S Barot; Punit B Parejiya; Hetal K Patel; Dharmik M Mehta; Pragna K Shelat
Journal:  Drug Deliv Transl Res       Date:  2012-12       Impact factor: 4.617

6.  Microemulsion-based gel of terbinafine for the treatment of onychomycosis: optimization of formulation using D-optimal design.

Authors:  Bhavesh S Barot; Punit B Parejiya; Hetal K Patel; Mukesh C Gohel; Pragna K Shelat
Journal:  AAPS PharmSciTech       Date:  2011-12-22       Impact factor: 3.246

7.  Pharmacological and pharmacokinetic studies with vitamin D-loaded nanoemulsions in asthma model.

Authors:  Tang Wei-hong; Guan Min-chang; Xu Zhen; Sun Jie
Journal:  Inflammation       Date:  2014-06       Impact factor: 4.092

8.  Formulation and statistical optimization of self-microemulsifying drug delivery system of eprosartan mesylate for improvement of oral bioavailability.

Authors:  Pankaj Dangre; Ritu Gilhotra; Shashikant Dhole
Journal:  Drug Deliv Transl Res       Date:  2016-10       Impact factor: 4.617

9.  A novel camptothecin derivative incorporated in nano-carrier induced distinguished improvement in solubility, stability and anti-tumor activity both in vitro and in vivo.

Authors:  Min Han; Cai-Xia He; Qiu-Li Fang; Xiao-Chun Yang; Yuan-Yuan Diao; Dong-Hang Xu; Qiao-Jun He; Yong-Zhou Hu; Wen-Quan Liang; Bo Yang; Jian-Qing Gao
Journal:  Pharm Res       Date:  2008-12-02       Impact factor: 4.200

10.  Anti-inflammatory effects of Z-ligustilide nanoemulsion.

Authors:  Zhaoji Ma; Lunhao Bai
Journal:  Inflammation       Date:  2013-04       Impact factor: 4.092

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