| Literature DB >> 16610400 |
Abstract
Concern has been raised about whether the fluid retention caused by thiazolidinediones (TZDs, ie, rosiglitazone and pioglitazone) can cause or exacerbate congestive heart failure. Although fluid retention is a worrisome side effect of TZDs, current evidence does not link fluid retention caused by TZDs with worsening heart function. TZDs have many benefits for patients with diabetes and can even be used cautiously in patients with mild heart failure, with careful monitoring of volume status.Entities:
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Year: 2006 PMID: 16610400 DOI: 10.3949/ccjm.73.4.390
Source DB: PubMed Journal: Cleve Clin J Med ISSN: 0891-1150 Impact factor: 2.321