Literature DB >> 16610258

[Celiac disease in the elderly: a case report].

Fiorenzo Baroni1, Maria Karin Ghisla, Roberto Leonardi, Vittorio Grassi.   

Abstract

Celiac disease is not a negligible cause of malabsorption in the elderly. Diarrhea, loss of weight and abdominal discomfort are often absent so that celiac disease has indeed a subtle, paucisymptomatic, course in the elderly. More than 50% of the patients have extraintestinal symptoms; only 10-40% have typical complaints pointing to small-intestinal biopsy. Elimination of gluten from diet is the cornerstone of the therapy. A 73-year-old woman with hyporexia, loss of weight, depression, bowel abnormalities and progressive deterioration of her abilities in the instrumental activities of daily living was referred to our department. Antigliadin and antiendomysial antibodies were present. A subsequent small-intestinal biopsy of the second and third portion of duodenum showed subtotal villous atrophy, increase of intra-epithelial lymphocytes as well as hyperplastic glands (type III Marsh score). All these pathological findings were compatible with celiac disease diagnosis so that a gluten-free diet was then initiated.

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Year:  2005        PMID: 16610258

Source DB:  PubMed          Journal:  Ann Ital Med Int        ISSN: 0393-9340


  1 in total

1.  Celiac disease: similar presentations in the elderly and young adults.

Authors:  Rupa Mukherjee; Ikenna Egbuna; Pardeep Brar; Lincoln Hernandez; Donald J McMahon; Elizabeth J Shane; Govind Bhagat; Peter H R Green
Journal:  Dig Dis Sci       Date:  2010-02-18       Impact factor: 3.199

  1 in total

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