Literature DB >> 16609796

Direct catalytic asymmetric anti-selective Mannich-type reactions.

Ismail Ibrahem1, Armando Córdova.   

Abstract

The simple chiral pyrrolidine catalyzed asymmetric anti-selective Mannich-type reaction is presented; the reaction gives the corresponding amino acid derivatives with 10:1- >19:1 dr and 97-99% ee.

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Year:  2006        PMID: 16609796     DOI: 10.1039/b602221a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Enantioselective organocatalytic aminomethylation of aldehydes: a role for ionic interactions and efficient access to beta2-amino acids.

Authors:  Yonggui Chi; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2006-05-31       Impact factor: 15.419

2.  Skeletally diverse small molecules using a build/couple/pair strategy.

Authors:  Takuya Uchida; Manuela Rodriquez; Stuart L Schreiber
Journal:  Org Lett       Date:  2009-04-02       Impact factor: 6.005

  2 in total

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