| Literature DB >> 16609676 |
K N Lai1.
Abstract
IgA nephropathy (IgAN), the most common glomerulonephritis worldwide, remains an important cause of end-stage renal failure. The pathology is characterized by mesangial deposition of IgA. The disease is now recognized as arising from anomalies of the IgA molecule and the kidneys are innocent bystanders. The immunochemical nature of the IgA molecule and its mesangial uptake command a pivotal role in the pathogenesis of IgAN.Entities:
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Year: 2006 PMID： 16609676 DOI： 10.1038/sj.ki.5000205
Source DB: PubMed Journal: Kidney Int ISSN： 0085-2538 Impact factor: 10.612