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Literature DB >> 16608248

Zeptogram-scale nanomechanical mass sensing.

Y T Yang¹, C Callegari, X L Feng, K L Ekinci, M L Roukes.

Abstract

Very high frequency (VHF) nanoelectromechanical systems (NEMS) provide unprecedented sensitivity for inertial mass sensing. We demonstrate in situ measurements in real time with mass noise floor approximately 20 zg. Our best mass resolution corresponds to approximately 7 zg, equivalent to approximately 30 xenon atoms or the mass of an individual 4 kDa molecule. Detailed analysis of the ultimate sensitivity of such devices based on these experimental results indicates that NEMS can ultimately provide inertial mass sensing of individual intact, electrically neutral macromolecules with single-Dalton (1 amu) resolution.

Entities: Disease

Mesh：

Substances：
Gases

Year: 2006 PMID： 16608248 DOI： 10.1021/nl052134m

Source DB: PubMed Journal: Nano Lett ISSN： 1530-6984 Impact factor: 11.189

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Cited

72 in total

1. Dynamic manipulation of nanomechanical resonators in the high-amplitude regime and non-volatile mechanical memory operation.

Authors: Mahmood Bagheri; Menno Poot; Mo Li; Wolfram P H Pernice; Hong X Tang
Journal: Nat Nanotechnol Date: 2011-10-23 Impact factor: 39.213

2. Frequency stabilization in nonlinear micromechanical oscillators.

Authors: Dario Antonio; Damián H Zanette; Daniel López
Journal: Nat Commun Date: 2012-05-01 Impact factor: 14.919

3. A nanomechanical mass sensor with yoctogram resolution.

Authors: J Chaste; A Eichler; J Moser; G Ceballos; R Rurali; A Bachtold
Journal: Nat Nanotechnol Date: 2012-04-01 Impact factor: 39.213

4. Flexure-FET biosensor to break the fundamental sensitivity limits of nanobiosensors using nonlinear electromechanical coupling.

Authors: Ankit Jain; Pradeep R Nair; Muhammad A Alam
Journal: Proc Natl Acad Sci U S A Date: 2012-05-23 Impact factor: 11.205

Zeptogram-scale nanomechanical mass sensing.

1. Dynamic manipulation of nanomechanical resonators in the high-amplitude regime and non-volatile mechanical memory operation.

2. Frequency stabilization in nonlinear micromechanical oscillators.

3. A nanomechanical mass sensor with yoctogram resolution.

4. Flexure-FET biosensor to break the fundamental sensitivity limits of nanobiosensors using nonlinear electromechanical coupling.

5. Nanomechanical mass sensing and stiffness spectrometry based on two-dimensional vibrations of resonant nanowires.

6. Energy dissipation in microfluidic beam resonators: Dependence on mode number.

7. Label-free imaging, detection, and mass measurement of single viruses by surface plasmon resonance.

8. Nonlinear tuning of microresonators for dynamic range enhancement.

Review 9. Tunable micro- and nanomechanical resonators.

10. Time, temperature, and load: the flaws of carbon nanotubes.