Mass probe-assisted ionization method for total analysis of biomolecules with electrospray ionization-mass spectrometry.

In this paper, we review the mass probes used for the derivation of a variety of biomolecules efficiently detected by the electrospray ionization-mass spectrometry and mass probe-assisted ionization method for total analysis and determination by consecutive detection with a single instrument. We describe mass probes for a variety of molecules including proteins, nucleobases, metallic cations, and other small molecules. Copyright 2006 The Japan Chemical Journal Forum and Wiley Periodicals, Inc.