| Literature DB >> 16604099 |
Abstract
The US Food and Drug Administration defines an Rx-to-OTC switch as over-the-counter (OTC) marketing of a drug product that was once a prescription (Rx) drug for the same indication, with the same strength, dose, duration of use, dosage form, population and route of administration. Here, we examine the rationale behind switches, the process of switches and historical case studies of switches in the United States to understand the factors for success and expected future trends.Mesh：
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Year: 2006 PMID： 16604099 DOI： 10.1038/nrd2028
Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694