Literature DB >> 16602727

Bilayer fibril formation by genetically engineered polypeptides: preparation and characterization.

Natalya I Topilina1, Seiichiro Higashiya, Narender Rana, Vladimir V Ermolenkov, Christopher Kossow, Autumn Carlsen, Silvana C Ngo, Christopher C Wells, Eric T Eisenbraun, Kathleen A Dunn, Igor K Lednev, Robert E Geer, Alain E Kaloyeros, John T Welch.   

Abstract

A de novo, genetically engineered 687 residue polypeptide expressed in E. coli has been found to form highly rectilinear, beta-sheet containing fibrillar structures. Tapping-mode atomic force microscopy, deep-UV Raman spectroscopy, and transmission electron microscopy definitively established the tendency of the fibrils to predominantly display an apparently planar bilayer or ribbon assemblage. The ordered self-assembly of designed, extremely repetitive, high molecular weight peptides is a harbinger of the utility of similar materials in nanoscience and engineering applications.

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Year:  2006        PMID： 16602727     DOI： 10.1021/bm0509016

Source DB:  PubMed          Journal:  Biomacromolecules        ISSN： 1525-7797            Impact factor:   6.988


  9 in total

1.  Evaluation of conformation and association behavior of multivalent alanine-rich polypeptides.

Authors:  Robin S Farmer; Ayben Top; Lindsey M Argust; Shuang Liu; Kristi L Kiick
Journal:  Pharm Res       Date:  2007-08-03       Impact factor: 4.200

2.  Reversible thermal denaturation of a 60-kDa genetically engineered beta-sheet polypeptide.

Authors:  Igor K Lednev; Vladimir V Ermolenkov; Seiichiro Higashiya; Ludmila A Popova; Natalya I Topilina; John T Welch
Journal:  Biophys J       Date:  2006-08-04       Impact factor: 4.033

3.  Multiple site-selective insertions of noncanonical amino acids into sequence-repetitive polypeptides.

Authors:  I-Lin Wu; Melissa A Patterson; Holly E Carpenter Desai; Ryan A Mehl; Gianluca Giorgi; Vincent P Conticello
Journal:  Chembiochem       Date:  2013-04-26       Impact factor: 3.164

Review 4.  Multivalent protein polymers with controlled chemical and physical properties.

Authors:  Ayben Top; Kristi L Kiick
Journal:  Adv Drug Deliv Rev       Date:  2010-06-01       Impact factor: 15.470

Review 5.  UV resonance Raman investigations of peptide and protein structure and dynamics.

Authors:  Sulayman A Oladepo; Kan Xiong; Zhenmin Hong; Sanford A Asher; Joseph Handen; Igor K Lednev
Journal:  Chem Rev       Date:  2012-02-15       Impact factor: 60.622

Review 6.  Engineering structure and function using thermoresponsive biopolymers.

Authors:  Martha K Pastuszka; J Andrew MacKay
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2015-06-26

7.  Cycloaddition-promoted self-assembly of a polymer into well-defined beta sheets and hierarchical nanofibrils.

Authors:  Ting-Bin Yu; Jane Z Bai; Zhibin Guan
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

8.  Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides.

Authors:  Andrew J Scotter; Meng Guo; Melanie M Tomczak; Margaret E Daley; Robert L Campbell; Richard J Oko; David A Bateman; Avijit Chakrabartty; Brian D Sykes; Peter L Davies
Journal:  BMC Struct Biol       Date:  2007-10-01

Review 9.  Fibrous Scaffolds From Elastin-Based Materials.

Authors:  Jose Carlos Rodriguez-Cabello; Israel Gonzalez De Torre; Miguel González-Pérez; Fernando González-Pérez; Irene Montequi
Journal:  Front Bioeng Biotechnol       Date:  2021-07-16
  9 in total

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