Literature DB >> 16602693

Pilot study using SELDI-TOF-MS based proteomic profile for the identification of diagnostic biomarkers of thyroid proliferative diseases.

R Suriano1, Y Lin, B T Ashok, S D Schaefer, S P Schantz, J Geliebter, R K Tiwari.   

Abstract

Biomarkers for thyroid cancer (TCa) lack specificity. To develop TCa specific biomarkers, SELDI-TOF-MS was used to examine the proteomic profile of biopsies obtained from papillary TCa along with adjacent normal tissue. Sixty-three potential biomarkers were categorized by univariate analysis into single biomarker candidates and segregated by multivariate analysis into normal and cancerous groups. Our studies demonstrate the sensitivity and reproducibility of this approach to detect biomarkers for TCa.

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Year:  2006        PMID: 16602693     DOI: 10.1021/pr050349r

Source DB:  PubMed          Journal:  J Proteome Res        ISSN: 1535-3893            Impact factor:   4.466


  6 in total

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Review 2.  Molecular Signature of Indeterminate Thyroid Lesions: Current Methods to Improve Fine Needle Aspiration Cytology (FNAC) Diagnosis.

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Journal:  Drug Deliv       Date:  2021-12       Impact factor: 6.419

5.  Discovery and identification of potential biomarkers of papillary thyroid carcinoma.

Authors:  Yuxia Fan; Linan Shi; Qiuliang Liu; Rui Dong; Qian Zhang; Shaobo Yang; Yingzhong Fan; Heying Yang; Peng Wu; Jiekai Yu; Shu Zheng; Fuquan Yang; Jiaxiang Wang
Journal:  Mol Cancer       Date:  2009-09-28       Impact factor: 27.401

6.  The evolution of biomarkers in thyroid cancer-from mass screening to a personalized biosignature.

Authors:  Raymon H Grogan; Elliot J Mitmaker; Orlo H Clark
Journal:  Cancers (Basel)       Date:  2010-05-20       Impact factor: 6.639

  6 in total

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