Literature DB >> 16600233

Polymorphisms of the peroxisome proliferator-activated receptor-gamma and its coactivator-1alpha genes in Chinese women with polycystic ovary syndrome.

Yong Wang1, Xiaoke Wu, Yunxia Cao, Long Yi, Haijian Fan, Jianxiu Chen.   

Abstract

The polymorphisms of the peroxisome proliferator-activated receptor-gamma (Pro12Ala) and its coactivator-1 (Gly482Ser) genes were investigated among 201 Chinese Han women with polycystic ovary syndrome (PCOS) and among 147 regularly cycling women as control subjects. We did not find statistically significant differences with peroxisome proliferator-activated receptor-gamma2 Pro12Ala and peroxisome proliferator-activated receptor-gamma-1alpha Gly482Ser polymorphism distributions between Chinese women with PCOS and controls, or with body mass index and reproductive hormones among various genotypic groups of PCOS, suggesting that these genetic mutants did not have an effect on the susceptibility to PCOS.

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Year:  2006        PMID： 16600233     DOI： 10.1016/j.fertnstert.2005.10.047

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  13 in total

1.  Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with polycystic ovary syndrome: a meta-analysis.

Authors:  Song-Tao Tang; Chang-Jiang Wang; Hai-Qin Tang; Wen-Jia Peng; You-Min Wang; Qiu Zhang
Journal:  Mol Biol Rep       Date:  2012-06-24       Impact factor: 2.316

Review 2.  MicroRNA in Ovarian Biology and Disease.

Authors:  Lynda K McGinnis; Lacey J Luense; Lane K Christenson
Journal:  Cold Spring Harb Perspect Med       Date:  2015-05-18       Impact factor: 6.915

3.  Genetic variants in peroxisome proliferator-activated receptor gamma influence insulin resistance and testosterone levels in normal women, but not those with polycystic ovary syndrome.

Authors:  Heath J Antoine; Marita Pall; Belynda C Trader; Yii-Der I Chen; Ricardo Azziz; Mark O Goodarzi
Journal:  Fertil Steril       Date:  2006-12-04       Impact factor: 7.329

Review 4.  Genetic variants associated with insulin signaling and glucose homeostasis in the pathogenesis of insulin resistance in polycystic ovary syndrome: a systematic review.

Authors:  Bhaskar Venkata Kameswara Subrahmanya Lakkakula; Maheswari Thangavelu; Usha Rani Godla
Journal:  J Assist Reprod Genet       Date:  2013-06-22       Impact factor: 3.412

5.  Peroxisome proliferator activated receptor gamma gene variants influence susceptibility and insulin related traits in Indian women with polycystic ovary syndrome.

Authors:  Nuzhat Shaikh; Ankur Mukherjee; Nalini Shah; Pervin Meherji; Srabani Mukherjee
Journal:  J Assist Reprod Genet       Date:  2013-06-09       Impact factor: 3.412

6.  A meta-analysis on the association between PPAR-γ Pro12Ala polymorphism and polycystic ovary syndrome.

Authors:  Junli He; Li Wang; Junhong Liu; Feng Liu; Xuliang Li
Journal:  J Assist Reprod Genet       Date:  2012-04-21       Impact factor: 3.412

7.  The association of Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 gene with the metabolic characteristics in Chinese women with polycystic ovary syndrome.

Authors:  Jiejin Yang; Hao Gong; Wei Liu; Tao Tao
Journal:  Int J Clin Exp Pathol       Date:  2013-08-15

8.  Peroxisome proliferator-activated receptor gamma rs1801282 C>G polymorphism is associated with polycystic ovary syndrome susceptibility: a meta-analysis involving 7,069 subjects.

Authors:  Sheng Zhang; Yafeng Wang; Heping Jiang; Chao Liu; Bin Sun; Shuchen Chen; Mingqiang Kang; Weifeng Tang
Journal:  Int J Clin Exp Med       Date:  2015-10-15

9.  The Genetic Basis of the Polycystic Ovary Syndrome: A Literature Review Including Discussion of PPAR-gamma.

Authors:  Ugur Unluturk; Ayla Harmanci; Cetin Kocaefe; Bulent O Yildiz
Journal:  PPAR Res       Date:  2007       Impact factor: 4.964

Review 10.  Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.

Authors:  M Simoni; C B Tempfer; B Destenaves; B C J M Fauser
Journal:  Hum Reprod Update       Date:  2008-07-04       Impact factor: 15.610
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