Literature DB >> 16600055

Addressing the challenges of cellular delivery and bioavailability of peptide nucleic acids (PNA).

Peter E Nielsen1.   

Abstract

Recent results on the cellular delivery of antisense peptide nucleic acids (PNA) via peptide conjugation is briefly discussed, in particular in the context of endosomal entrapment and escape.

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Year:  2006        PMID： 16600055     DOI： 10.1017/S0033583506004148

Source DB:  PubMed          Journal:  Q Rev Biophys        ISSN： 0033-5835            Impact factor:   5.318


  19 in total

1.  Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids.

Authors:  Pankaj Gupta; Oluwatoyosi Muse; Eriks Rozners
Journal:  Biochemistry       Date:  2011-12-20       Impact factor: 3.162

2.  Design of embedded chimeric peptide nucleic acids that efficiently enter and accurately reactivate gene expression in vivo.

Authors:  Joy Chen; Kenneth R Peterson; Camelia Iancu-Rubin; James J Bieker
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-13       Impact factor: 11.205

Review 3.  pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents.

Authors:  Oleg A Andreev; Donald M Engelman; Yana K Reshetnyak
Journal:  Mol Membr Biol       Date:  2010-10-13       Impact factor: 2.857

4.  STAT3 inhibition in prostate and pancreatic cancer lines by STAT3 binding sequence oligonucleotides: differential activity between 5' and 3' ends.

Authors:  H Dan Lewis; Ashley Winter; Thomas F Murphy; Snehlata Tripathi; Virendra N Pandey; Beverly E Barton
Journal:  Mol Cancer Ther       Date:  2008-06       Impact factor: 6.261

Review 5.  Nanotechnology for delivery of peptide nucleic acids (PNAs).

Authors:  Anisha Gupta; Raman Bahal; Meera Gupta; Peter M Glazer; W Mark Saltzman
Journal:  J Control Release       Date:  2016-01-08       Impact factor: 9.776

6.  Inhibiting gene expression with peptide nucleic acid (PNA)--peptide conjugates that target chromosomal DNA.

Authors:  Jiaxin Hu; David R Corey
Journal:  Biochemistry       Date:  2007-05-31       Impact factor: 3.162

7.  Sequence selective recognition of double-stranded RNA at physiologically relevant conditions using PNA-peptide conjugates.

Authors:  Oluwatoyosi Muse; Thomas Zengeya; Juddy Mwaura; Dziyana Hnedzko; Dennis W McGee; Christof T Grewer; Eriks Rozners
Journal:  ACS Chem Biol       Date:  2013-06-12       Impact factor: 5.100

8.  Synthesis of conformationally preorganized and cell-permeable guanidine-based gamma-peptide nucleic acids (gammaGPNAs).

Authors:  Bichismita Sahu; Venugopal Chenna; Kira L Lathrop; Sufi M Thomas; Gerald Zon; Kenneth J Livak; Danith H Ly
Journal:  J Org Chem       Date:  2009-02-20       Impact factor: 4.354

9.  Recent advances in chemical modification of Peptide nucleic acids.

Authors:  Eriks Rozners
Journal:  J Nucleic Acids       Date:  2012-09-06

10.  An in vitro translation, selection and amplification system for peptide nucleic acids.

Authors:  Yevgeny Brudno; Michael E Birnbaum; Ralph E Kleiner; David R Liu
Journal:  Nat Chem Biol       Date:  2009-12-27       Impact factor: 15.040
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