OBJECTIVES: To describe the characteristics of fundus fluorescein angiography in retinopathy of prematurity (ROP) and to explore the possible benefits of fundus fluorescein angiography over conventional indirect ophthalmoscopy in the screening for and management of ROP. PATIENTS AND METHODS: Beginning in January 2003, 23 consecutive patients were recruited for a nonrandomized, investigational trial. Fifty-one sessions of fundus fluorescein angiography were performed as part of ROP screening. RESULTS: Fundus fluorescein angiography caused no adverse effect. Clear angiograms were easily obtained. There was delayed arm-to-eye fluorescein transit. Leakage of fluorescein was observed in all stage 2 and stage 3 ROP. The leakage resolved soon after treatment. Arteriovenous tufts were found far posterior to the ROP ridge and were a feature of severe ROP. CONCLUSIONS: Some vascular pathology observed on angiograms cannot be seen on indirect ophthalmoscopy. There was delayed arm-to-eye transit and fluorescein transit within the eyes. Fundus fluorescein angiography allows more objective assessment of disease stage and zone. Regression of ROP is clearly observed on fundus fluorescein angiography.
OBJECTIVES: To describe the characteristics of fundus fluorescein angiography in retinopathy of prematurity (ROP) and to explore the possible benefits of fundus fluorescein angiography over conventional indirect ophthalmoscopy in the screening for and management of ROP. PATIENTS AND METHODS: Beginning in January 2003, 23 consecutive patients were recruited for a nonrandomized, investigational trial. Fifty-one sessions of fundus fluorescein angiography were performed as part of ROP screening. RESULTS: Fundus fluorescein angiography caused no adverse effect. Clear angiograms were easily obtained. There was delayed arm-to-eye fluorescein transit. Leakage of fluorescein was observed in all stage 2 and stage 3 ROP. The leakage resolved soon after treatment. Arteriovenous tufts were found far posterior to the ROP ridge and were a feature of severe ROP. CONCLUSIONS: Some vascular pathology observed on angiograms cannot be seen on indirect ophthalmoscopy. There was delayed arm-to-eye transit and fluorescein transit within the eyes. Fundus fluorescein angiography allows more objective assessment of disease stage and zone. Regression of ROP is clearly observed on fundus fluorescein angiography.
Authors: Linda A Cernichiaro-Espinosa; Francisco J Olguin-Manriquez; Andree Henaine-Berra; Gerardo Garcia-Aguirre; Hugo Quiroz-Mercado; Maria A Martinez-Castellanos Journal: Int Ophthalmol Date: 2016-01-14 Impact factor: 2.031
Authors: Dana Darwish; Ru-Ik Chee; Samir N Patel; Karyn Jonas; Susan Ostmo; J Peter Campbell; Michael F Chiang; R V Paul Chan Journal: Asia Pac J Ophthalmol (Phila) Date: 2018-05-29
Authors: Samir N Patel; Michael A Klufas; Michael C Ryan; Karyn E Jonas; Susan Ostmo; Maria Ana Martinez-Castellanos; Audina M Berrocal; Michael F Chiang; R V Paul Chan Journal: Am J Ophthalmol Date: 2015-01-28 Impact factor: 5.258
Authors: L Consuelo Zepeda-Romero; Aldo A Oregon-Miranda; Dalia S Lizarraga-Barrón; Oscar Gutiérrez-Camarena; Alonso Meza-Anguiano; José Alfonso Gutiérrez-Padilla Journal: Graefes Arch Clin Exp Ophthalmol Date: 2013-04-02 Impact factor: 3.117
Authors: Michael A Klufas; Samir N Patel; Michael C Ryan; Mrinali Patel Gupta; Karyn E Jonas; Susan Ostmo; Maria Ana Martinez-Castellanos; Audina M Berrocal; Michael F Chiang; R V Paul Chan Journal: Ophthalmology Date: 2015-05-28 Impact factor: 12.079