Literature DB >> 16598619

[Three-dimensional vectorcardiography to predict CRT-responder].

W Koglek1, J Brandl, A Oberbichler, K Schmidt, G Grimm, C Butter.   

Abstract

Cardiac resynchronization therapy (CRT) is an accepted treatment for congestive heart failure (NYHA III-IV), but a substantial number of patients show no response to therapy. LBB, QRS width and echocardiographic measurements are parameters for indication, but they are not valid to predict hemodynamic response. A new method based on vector ECG analysis can deliver additional information, such as: parts or areas with late excitation, and with slow or fast depolarization speed. Electrical excitation is a prerequisite for contraction; this leads to the hypothesis that areas with late electrical activation will contract later. Algorithms for analysis of the vector ECG (determination of the vector -- time, area and speed) may help to identify responders and non-responders.

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Year:  2006        PMID: 16598619     DOI: 10.1007/s00399-006-1105-9

Source DB:  PubMed          Journal:  Herzschrittmacherther Elektrophysiol        ISSN: 0938-7412


  1 in total

Review 1.  Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells.

Authors:  T F McDonald; S Pelzer; W Trautwein; D J Pelzer
Journal:  Physiol Rev       Date:  1994-04       Impact factor: 37.312

  1 in total
  2 in total

1.  [Optimized programming during cardiac resynchronization therapy].

Authors:  T Deneke; B Lemke; M Horlitz; A Drüke; A Mügge; P H Grewe; T Lawo
Journal:  Herzschrittmacherther Elektrophysiol       Date:  2008-03

2.  Baseline vectorcardiography as a predictor of invasively determined acute hemodynamic response to cardiac resynchronization therapy.

Authors:  Thomas Schau; Walter Koglek; Josef Brandl; Martin Seifert; Jürgen Meyhöfer; Michael Neuss; Georg Grimm; Robert Bitschnau; Christian Butter
Journal:  Clin Res Cardiol       Date:  2012-09-23       Impact factor: 5.460

  2 in total

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