Keiichi Mitarai1, Fumi Gomi, Yasuo Tano. 1. Department of Ophthalmology, Osaka University, Graduate School of Medicine, Room E7, 2-2 Yamadaoka Suita, Osaka, Japan.
Abstract
PURPOSE: The purpose of this study was to evaluate three-dimensional optical coherence tomographic findings at the leakage point on fluorescein angiography in central serous chorioretinopathy (CSC) with OCT-ophthalmoscope. METHODS: Twenty-seven eyes of 26 patients (23 men, three women; mean age, 50 years; range, 30-72) diagnosed with CSC were examined with OCT-ophthalmoscope, and transverse and longitudinal images were compared with fundus and fluorescein angiography findings. RESULTS: Transverse images (C-scan) clearly showed serous retinal detachment in all eyes and irregular lesions in retinal pigment epithelium (RPE) in 26 of 27 eyes (96%). These results agreed with the location of lesions in areas of fluorescein dye leakage on fluorescein angiography. Longitudinal images (B-scan) of irregular RPE lesions in transverse images showed RPE detachment (PED) in 17 eyes (63%), small protrusion of the RPE layer in five eyes (19%), and rough RPE layer in four eyes (15%). CONCLUSIONS: OCT-ophthalmoscope detects morphologic changes easily and noninvasively at the point of dye leakage in eyes with CSC.
PURPOSE: The purpose of this study was to evaluate three-dimensional optical coherence tomographic findings at the leakage point on fluorescein angiography in central serous chorioretinopathy (CSC) with OCT-ophthalmoscope. METHODS: Twenty-seven eyes of 26 patients (23 men, three women; mean age, 50 years; range, 30-72) diagnosed with CSC were examined with OCT-ophthalmoscope, and transverse and longitudinal images were compared with fundus and fluorescein angiography findings. RESULTS: Transverse images (C-scan) clearly showed serous retinal detachment in all eyes and irregular lesions in retinal pigment epithelium (RPE) in 26 of 27 eyes (96%). These results agreed with the location of lesions in areas of fluorescein dye leakage on fluorescein angiography. Longitudinal images (B-scan) of irregular RPE lesions in transverse images showed RPE detachment (PED) in 17 eyes (63%), small protrusion of the RPE layer in five eyes (19%), and rough RPE layer in four eyes (15%). CONCLUSIONS:OCT-ophthalmoscope detects morphologic changes easily and noninvasively at the point of dye leakage in eyes with CSC.
Authors: Adrian Gh Podoleanu; George M Dobre; Radu G Cucu; Richard Rosen; Patricia Garcia; Juan Nieto; Daniel Will; Ronald Gentile; Thomas Muldoon; Joseph Walsh; Lawrence A Yannuzzi; Yale Fisher; Dennis Orlock; Rishard Weitz; John A Rogers; Shane Dunne; Aaron Boxer Journal: J Biomed Opt Date: 2004 Jan-Feb Impact factor: 3.170
Authors: M R Hee; C A Puliafito; C Wong; E Reichel; J S Duker; J S Schuman; E A Swanson; J G Fujimoto Journal: Am J Ophthalmol Date: 1995-07 Impact factor: 5.258
Authors: Matthew G Field; Victor M Elner; Seung Park; Richard Hackel; John R Heckenlively; Susan G Elner; Howard R Petty Journal: Retina Date: 2009-09 Impact factor: 4.256