Literature DB >> 16595459

Use of cost-effectiveness analysis to evaluate new technologies in orthopaedics. The case of alternative bearing surfaces in total hip arthroplasty.

Kevin J Bozic1, Saam Morshed, Marc D Silverstein, Harry E Rubash, James G Kahn.   

Abstract

BACKGROUND: Alternative bearing surfaces offer the potential to reduce wear and improve implant longevity following total hip arthroplasty. However, these technologies are associated with higher costs, the potential for unintended consequences, and uncertain benefits in terms of long-term survival of the implants. The purpose of this study was to evaluate the cost-effectiveness of the use of alternative bearings in total hip arthroplasty.
METHODS: A decision-analysis model was constructed to estimate the cost-effectiveness of the use of alternative bearings for patients undergoing total hip arthroplasty. Model inputs, including costs, clinical outcome probabilities, and health utility values, were derived from a review of the literature. Sensitivity analyses were performed to evaluate the impact of patient age at the time of surgery, implant costs, and reductions in revision rates on the cost-effectiveness of alternate bearing surfaces.
RESULTS: In a population of fifty-year-old patients, use of an alternative bearing with an incremental cost of 2000 dollars would be cost-saving over the individual's lifetime if it were associated with at least a 19% reduction in the twenty-year implant failure rate when compared with the failure rate for a conventional bearing. In a population of patients over the age of sixty-three years, the same implant would be associated with higher lifetime costs than would a conventional bearing, regardless of the presumed reduction in the revision rate. Conversely, an alternative bearing that adds only 500 dollars to the cost of a conventional total hip arthroplasty could be cost-saving in a population of patients over the age of sixty-five years, even if it were associated with only a modest reduction in the revision rate. In a population of patients over the age of seventy-five years, no alternative bearing would be associated with lifetime cost-savings, regardless of the cost or the presumed reduction in the revision rate.
CONCLUSIONS: The cost-effectiveness of alternative bearings is highly dependent on the age of the patient at the time of surgery, the cost of the implant, and the associated reduction in the probability of revision relative to that associated with conventional bearings. Our findings provide a quantitative rationale for requiring greater evidence of effectiveness in reducing the probability of implant failure when more costly alternative bearings are being considered, particularly for older patients.

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Mesh:

Year:  2006        PMID: 16595459     DOI: 10.2106/JBJS.E.00614

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  28 in total

1.  Healthcare technology and technology assessment.

Authors:  James H Herndon; Raymond Hwang; K J Bozic; K H Bozic
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2.  Ceramic on crosslinked polyethylene in total hip replacement: any better than metal on crosslinked polyethylene?

Authors:  John J Callaghan; Steve S Liu
Journal:  Iowa Orthop J       Date:  2009

3.  Surgical treatment and rehabilitation of combined complex ligament injuries.

Authors:  Richard L Romeyn; Jason Jennings; George J Davies
Journal:  N Am J Sports Phys Ther       Date:  2008-11

Review 4.  Current status of cost utility analyses in total joint arthroplasty: a systematic review.

Authors:  Benedict U Nwachukwu; Kevin J Bozic; William W Schairer; Jaime L Bernstein; David S Jevsevar; Robert G Marx; Douglas E Padgett
Journal:  Clin Orthop Relat Res       Date:  2014-09-30       Impact factor: 4.176

5.  Is there a rationale to use highly cross-linked polyethylene in posterior-stabilized total knee arthroplasty?

Authors:  Lisa Renner; Martin Faschingbauer; Friedrich Boettner
Journal:  Ann Transl Med       Date:  2015-04

6.  What Are the Strength of Recommendations and Methodologic Reporting in Health Economic Studies in Orthopaedic Surgery?

Authors:  Eric C Makhni; Michael E Steinhaus; Eric Swart; Kevin J Bozic
Journal:  Clin Orthop Relat Res       Date:  2015-05-30       Impact factor: 4.176

7.  Assessing the value of a total joint replacement.

Authors:  David B Bumpass; Ryan M Nunley
Journal:  Curr Rev Musculoskelet Med       Date:  2012-12

8.  Do the potential benefits of metal-on-metal hip resurfacing justify the increased cost and risk of complications?

Authors:  Kevin J Bozic; Christine M Pui; Matthew J Ludeman; Thomas P Vail; Marc D Silverstein
Journal:  Clin Orthop Relat Res       Date:  2010-09       Impact factor: 4.176

Review 9.  The cost-effectiveness of total joint arthroplasty: a systematic review of published literature.

Authors:  Meghan E Daigle; Alexander M Weinstein; Jeffrey N Katz; Elena Losina
Journal:  Best Pract Res Clin Rheumatol       Date:  2012-10       Impact factor: 4.098

10.  Users' guide to the orthopaedic literature: what is a cost-effectiveness analysis?

Authors:  Stephanie Tanner; Sheila Sprague; Kyle Jeray
Journal:  Indian J Orthop       Date:  2008-04       Impact factor: 1.251

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