Literature DB >> 16595320

Changes in tobacco smoking following treatment for cocaine dependence.

Ashwin A Patkar1, Paolo Mannelli, Kathleen Peindl, Heather W Murray, Bradley Meier, Frank T Leone.   

Abstract

Incorporation of smoking cessation into cocaine treatment programs remains a challenge. A major concern is that cocaine abusers may tend to substitute one drug for the other. If this is true, successful treatment of cocaine abuse should lead to an increase in tobacco smoking. We compared tobacco smoking at admission, end of treatment and 9-month follow up for 168 crack cocaine dependent patients entering a 12-week outpatient treatment program for substance abuse. Smoking cessation was not a part of treatment. As expected cocaine patients improved with treatment and showed significant reduction in scores on the Addiction Severity Index (ASI). There were no significant changes in number of cigarettes smoked per day or scores on the Fagerstrom Test for Nicotine dependence (FTND) from baseline to end of treatment or follow-up. Also, there were no differences in the proportions of nonsmokers and smokers who changed their smoking habits over the treatment and follow up period. At follow up subjects who were abstinent as well as those using cocaine showed no changes in tobacco smoking. There is no evidence that reduction in crack cocaine smoking following treatment is accompanied by an increase in tobacco smoking. It appears that concerns over tobacco being substituted for cocaine may be unfounded in this population.

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Year:  2006        PMID: 16595320     DOI: 10.1080/00952990500479209

Source DB:  PubMed          Journal:  Am J Drug Alcohol Abuse        ISSN: 0095-2990            Impact factor:   3.829


  19 in total

1.  Chronic cigarette smoking modulates injury and short-term recovery of the medial temporal lobe in alcoholics.

Authors:  Stefan Gazdzinski; Timothy C Durazzo; Ping-Hong Yeh; Dawn Hardin; Peter Banys; Dieter J Meyerhoff
Journal:  Psychiatry Res       Date:  2008-02-28       Impact factor: 3.222

2.  Evaluating Nicotine Craving, Withdrawal, and Substance Use as Mediators of Smoking Cessation in Cocaine- and Methamphetamine-Dependent Patients.

Authors:  Joshua C Magee; Daniel F Lewis; Theresa Winhusen
Journal:  Nicotine Tob Res       Date:  2015-06-05       Impact factor: 4.244

3.  Immune system inflammation in cocaine dependent individuals: implications for medications development.

Authors:  Helen C Fox; Carrol D'Sa; Anne Kimmerling; Kristen M Siedlarz; Keri L Tuit; Raymond Stowe; Rajita Sinha
Journal:  Hum Psychopharmacol       Date:  2012-03       Impact factor: 1.672

4.  The influence of smoking cigarettes on the high and desire for cocaine among active cocaine users.

Authors:  Alex J Brewer; James J Mahoney; Chandra S Nerumalla; Thomas F Newton; Richard De La Garza
Journal:  Pharmacol Biochem Behav       Date:  2013-03-27       Impact factor: 3.533

5.  Sex differences in guanfacine effects on drug craving and stress arousal in cocaine-dependent individuals.

Authors:  Helen C Fox; Peter T Morgan; Rajita Sinha
Journal:  Neuropsychopharmacology       Date:  2014-01-07       Impact factor: 7.853

6.  Decreases in smoking during treatment for methamphetamine-use disorders: preliminary evidence.

Authors:  Sterling McPherson; Michael Orr; Crystal Lederhos; Michael McDonell; Emily Leickly; Katherine Hirchak; Oladunni A Oluwoye; Sean M Murphy; Matthew Layton; John M Roll
Journal:  Behav Pharmacol       Date:  2018-06       Impact factor: 2.293

Review 7.  Genetics of schizophrenia and smoking: an approach to studying their comorbidity based on epidemiological findings.

Authors:  Jose de Leon; Francisco J Diaz
Journal:  Hum Genet       Date:  2011-12-22       Impact factor: 4.132

Review 8.  The role of guanfacine as a therapeutic agent to address stress-related pathophysiology in cocaine-dependent individuals.

Authors:  Helen Fox; Rajita Sinha
Journal:  Adv Pharmacol       Date:  2014

9.  The effects of exogenous progesterone on drug craving and stress arousal in cocaine dependence: impact of gender and cue type.

Authors:  Helen C Fox; Mehmet Sofuoglu; Peter T Morgan; Keri L Tuit; Rajita Sinha
Journal:  Psychoneuroendocrinology       Date:  2013-01-29       Impact factor: 4.905

10.  Interactive effects of ethanol and nicotine on learning in C57BL/6J mice depend on both dose and duration of treatment.

Authors:  Danielle Gulick; Thomas J Gould
Journal:  Psychopharmacology (Berl)       Date:  2007-10-30       Impact factor: 4.530

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