Literature DB >> 16595244

Letrozole induction of ovulation in women with clomiphene citrate-resistant polycystic ovary syndrome may not depend on the period of infertility, the body mass index, or the luteinizing hormone/follicle-stimulating hormone ratio.

Aboubakr Elnashar1, Hany Fouad, Magy Eldosoky, Naser Saeid.   

Abstract

Letrozole induction of ovulation in clomiphene citrate-resistant women with polycystic ovary syndrome is associated with an ovulation rate of 54.6% and pregnancy rate of 25%. There was no significant difference between letrozole responders and nonresponders in age, period of infertility, body mass index, waist circumference, LH, FSH, or LH/FSH ratio.

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Year:  2006        PMID: 16595244     DOI: 10.1016/j.fertnstert.2005.08.016

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  14 in total

1.  The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome.

Authors:  Richard S Legro; Allen R Kunselman; Robert G Brzyski; Peter R Casson; Michael P Diamond; William D Schlaff; Gregory M Christman; Christos Coutifaris; Hugh S Taylor; Esther Eisenberg; Nanette Santoro; Heping Zhang
Journal:  Contemp Clin Trials       Date:  2012-01-13       Impact factor: 2.226

Review 2.  Potential of aromatase inhibitors for ovulation and superovulation induction in infertile women.

Authors:  Mohamed F M Mitwally; Robert F Casper
Journal:  Drugs       Date:  2006       Impact factor: 9.546

3.  Comparison of letrozole with continuous gonadotropins and clomiphene-gonadotropin combination for ovulation induction in 1387 PCOS women after clomiphene citrate failure: a randomized prospective clinical trial.

Authors:  Ashalatha Ganesh; Sourendra Kant Goswami; Ratna Chattopadhyay; Koel Chaudhury; Baidyanath Chakravarty
Journal:  J Assist Reprod Genet       Date:  2009-01-07       Impact factor: 3.412

4.  Letrozole or clomiphene citrate as first line for anovulatory infertility: a debate.

Authors:  Mohan S Kamath; Korula George
Journal:  Reprod Biol Endocrinol       Date:  2011-06-21       Impact factor: 5.211

5.  Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate-resistant polycystic ovary syndrome.

Authors:  Wei Liu; Shengnan Dong; Yumei Li; Lihong Shi; Wei Zhou; Yingling Liu; Jie Liu; Yazhong Ji
Journal:  Exp Ther Med       Date:  2015-08-19       Impact factor: 2.447

6.  Letrozole as the first-line treatment of infertile women with poly cystic ovarian syndrome (PCOS) compared with clomiphene citrate: A clinical trial.

Authors:  Ataollah Ghahiri; Neda Mogharehabed; Mahboobeh Mamourian
Journal:  Adv Biomed Res       Date:  2016-01-29

Review 7.  Use of letrozole in assisted reproduction: a systematic review and meta-analysis.

Authors:  Antonio Requena; Julio Herrero; José Landeras; Esperanza Navarro; José L Neyro; Cristina Salvador; Rosa Tur; Justo Callejo; Miguel A Checa; Magí Farré; Juan J Espinós; Francesc Fábregues; María Graña-Barcia
Journal:  Hum Reprod Update       Date:  2008-09-23       Impact factor: 15.610

8.  Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.

Authors:  Masomeh Hajishafiha; Meisam Dehghan; Nazila Kiarang; Nahideh Sadegh-Asadi; Seyed Navid Shayegh; Mohammad Ghasemi-Rad
Journal:  Drug Des Devel Ther       Date:  2013-12-03       Impact factor: 4.162

9.  Effects of simvastatin pretreatment on clomiphene response in clomiphene - resistant women with polycystic ovary syndrome.

Authors:  Azam Azargoon; Raheb Ghorbani; Zahra Faraji
Journal:  J Family Reprod Health       Date:  2013-12

10.  Comparison of the effectiveness of clomiphene citrate, tamoxifen and letrozole in ovulation induction in infertility due to isolated unovulation.

Authors:  Fariba Seyedoshohadaei; Farnaz Zandvakily; Shole Shahgeibi
Journal:  Iran J Reprod Med       Date:  2012-11
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