Literature DB >> 16595154

Principles: when there should be no difference--how to fail to reject the null hypothesis.

Michael J Lew1.   

Abstract

It is common to perform experiments in which a 'success' is claimed when the null hypothesis is discarded. However, there is a category of experiment that has become important in which a success is when the null hypothesis is not rejected. Failing to discard the null hypothesis is different from proving it to be valid, a distinction that is particularly important in experiments in which any inadequacy of experimental design or implementation enhances the likelihood of a success. The appropriate analysis of such experiments tests for evidence of the validity of the null hypothesis rather than simply failing to find evidence against it.

Mesh:

Year:  2006        PMID: 16595154     DOI: 10.1016/j.tips.2006.03.006

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN: 0165-6147            Impact factor:   14.819


  3 in total

1.  Good statistical practice in pharmacology. Problem 2.

Authors:  M Lew
Journal:  Br J Pharmacol       Date:  2007-07-09       Impact factor: 8.739

2.  Rosuvastatin ameliorates the development of pulmonary arterial hypertension in the transgenic (mRen2)27 rat.

Authors:  Vincent G DeMarco; Javad Habibi; Adam T Whaley-Connell; Rebecca I Schneider; James R Sowers; Bradley T Andresen; Alex A Gutweiler; Lixin Ma; Megan S Johnson; Carlos M Ferrario; Kevin C Dellsperger
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-07-24       Impact factor: 4.733

3.  Treatment of displaced transverse fractures of the patella: modified tension band wiring technique with or without augmented circumferential cerclage wire fixation.

Authors:  Tien-Yu Yang; Tsan-Wen Huang; Po-Yao Chuang; Kuo-Chin Huang
Journal:  BMC Musculoskelet Disord       Date:  2018-05-24       Impact factor: 2.362

  3 in total

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