Literature DB >> 16582513

[Tumor metastasis and MMP inhibitor].

Hiroshi Sato1.   

Abstract

Matrix metalloproteinase (MMP) plays important roles in tumor invasion and metastasis by degrading extracellular matrix components including collagen. Clinical trials of MMP inhibitor drugs have been carried out, however, they were not always as successful as expected.

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Year:  2006        PMID： 16582513     DOI： CliCa0604621626

Source DB:  PubMed          Journal:  Clin Calcium        ISSN： 0917-5857


  3 in total

1.  Mechanisms of pyruvate kinase M2 isoform inhibits cell motility in hepatocellular carcinoma cells.

Authors:  Yan-Ling Chen; Jun-Jiao Song; Xiao-Chun Chen; Wei Xu; Qiang Zhi; Yun-Peng Liu; Hong-Zhi Xu; Jin-Shui Pan; Jian-Lin Ren; Bayasi Guleng
Journal:  World J Gastroenterol       Date:  2015-08-14       Impact factor: 5.742

2.  New Strategies for the Next Generation of Matrix-Metalloproteinase Inhibitors: Selectively Targeting Membrane-Anchored MMPs with Therapeutic Antibodies.

Authors:  Laetitia Devy; Daniel T Dransfield
Journal:  Biochem Res Int       Date:  2010-10-28

3.  Surface α-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target.

Authors:  Kuan-Chung Hsiao; Neng-Yao Shih; Hsun-Lang Fang; Tze-Sing Huang; Ching-Chuan Kuo; Pei-Yi Chu; Yi-Mei Hung; Shao-Wen Chou; Yi-Yuan Yang; Gee-Chen Chang; Ko-Jiunn Liu
Journal:  PLoS One       Date:  2013-07-19       Impact factor: 3.240
  3 in total

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