Literature DB >> 16581764

Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.

Kevin Wilhelmsen1, Sandy H M Litjens, Arnoud Sonnenberg.   

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Year:  2006        PMID: 16581764      PMCID: PMC1446957          DOI: 10.1128/MCB.26.8.2877-2886.2006

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


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  102 in total

1.  Cooperative signaling between alpha(6)beta(4) integrin and ErbB-2 receptor is required to promote phosphatidylinositol 3-kinase-dependent invasion.

Authors:  D Gambaletta; A Marchetti; L Benedetti; A M Mercurio; A Sacchi; R Falcioni
Journal:  J Biol Chem       Date:  2000-04-07       Impact factor: 5.157

2.  Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice.

Authors:  Karine Raymond; Maaike Kreft; Hans Janssen; Jero Calafat; Arnoud Sonnenberg
Journal:  J Cell Sci       Date:  2005-03-01       Impact factor: 5.285

3.  Novel ITGB4 mutations in lethal and nonlethal variants of epidermolysis bullosa with pyloric atresia: missense versus nonsense.

Authors:  L Pulkkinen; F Rouan; L Bruckner-Tuderman; R Wallerstein; M Garzon; T Brown; L Smith; W Carter; J Uitto
Journal:  Am J Hum Genet       Date:  1998-11       Impact factor: 11.025

4.  Interaction of BP180 (type XVII collagen) and alpha6 integrin is necessary for stabilization of hemidesmosome structure.

Authors:  S B Hopkinson; K Findlay; G W deHart; J C Jones
Journal:  J Invest Dermatol       Date:  1998-12       Impact factor: 8.551

5.  Integrin beta4 signaling promotes tumor angiogenesis.

Authors:  Sotiris N Nikolopoulos; Pamela Blaikie; Toshiaki Yoshioka; Wenjun Guo; Filippo G Giancotti
Journal:  Cancer Cell       Date:  2004-11       Impact factor: 31.743

6.  The alpha3 laminin subunit, alpha6beta4 and alpha3beta1 integrin coordinately regulate wound healing in cultured epithelial cells and in the skin.

Authors:  L E Goldfinger; S B Hopkinson; G W deHart; S Collawn; J R Couchman; J C Jones
Journal:  J Cell Sci       Date:  1999-08       Impact factor: 5.285

7.  Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells.

Authors:  I Rabinovitz; A Toker; A M Mercurio
Journal:  J Cell Biol       Date:  1999-09-06       Impact factor: 10.539

8.  Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding.

Authors:  D Geerts; L Fontao; M G Nievers; R Q Schaapveld; P E Purkis; G N Wheeler; E B Lane; I M Leigh; A Sonnenberg
Journal:  J Cell Biol       Date:  1999-10-18       Impact factor: 10.539

9.  p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB.

Authors:  R E Bachelder; M J Ribick; A Marchetti; R Falcioni; S Soddu; K R Davis; A M Mercurio
Journal:  J Cell Biol       Date:  1999-11-29       Impact factor: 10.539

10.  Thymocyte contact or monoclonal antibody-mediated clustering of 3beta1 or 6beta4 integrins activate interleukin-6 (IL-6) transcription factors (NF-kappaB and NF-IL6) and IL-6 production in human thymic epithelial cells.

Authors:  D Ramarli; M T Scupoli; E Fiorini; O Poffe; M Brentegani; A Villa; G Cecchini; G Tridente; P C Marchisio
Journal:  Blood       Date:  1998-11-15       Impact factor: 22.113

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  52 in total

1.  Penfluridol: An Antipsychotic Agent Suppresses Metastatic Tumor Growth in Triple-Negative Breast Cancer by Inhibiting Integrin Signaling Axis.

Authors:  Alok Ranjan; Parul Gupta; Sanjay K Srivastava
Journal:  Cancer Res       Date:  2015-12-01       Impact factor: 12.701

Review 2.  Scratching the surface of skin development.

Authors:  Elaine Fuchs
Journal:  Nature       Date:  2007-02-22       Impact factor: 49.962

3.  EGF-induced MAPK signaling inhibits hemidesmosome formation through phosphorylation of the integrin {beta}4.

Authors:  Evelyne Frijns; Norman Sachs; Maaike Kreft; Kevin Wilhelmsen; Arnoud Sonnenberg
Journal:  J Biol Chem       Date:  2010-09-24       Impact factor: 5.157

4.  Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes.

Authors:  José M de Pereda; M Pilar Lillo; Arnoud Sonnenberg
Journal:  EMBO J       Date:  2009-02-26       Impact factor: 11.598

Review 5.  Basement membranes in skin: unique matrix structures with diverse functions?

Authors:  Dirk Breitkreutz; Nicolae Mirancea; Roswitha Nischt
Journal:  Histochem Cell Biol       Date:  2009-03-31       Impact factor: 4.304

Review 6.  Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1.

Authors:  Yoshikazu Takada; Yoko K Takada; Masaaki Fujita
Journal:  Cytokine Growth Factor Rev       Date:  2017-02-03       Impact factor: 7.638

7.  Interaction of nectin-like molecule 2 with integrin alpha6beta4 and inhibition of disassembly of integrin alpha6beta4 from hemidesmosomes.

Authors:  Kiyohito Mizutani; Satoshi Kawano; Akihiro Minami; Masazumi Waseda; Wataru Ikeda; Yoshimi Takai
Journal:  J Biol Chem       Date:  2011-08-31       Impact factor: 5.157

8.  Integrin α6β4 in colorectal cancer.

Authors:  Jean-François Beaulieu
Journal:  World J Gastrointest Pathophysiol       Date:  2010-04-15

9.  Integrin-blocking antibodies delay keratinocyte re-epithelialization in a human three-dimensional wound healing model.

Authors:  Christophe Egles; Heather A Huet; Furkan Dogan; Sam Cho; Shumin Dong; Avi Smith; Elana B Knight; Karen R McLachlan; Jonathan A Garlick
Journal:  PLoS One       Date:  2010-05-21       Impact factor: 3.240

Review 10.  Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets.

Authors:  Christopher S Stipp
Journal:  Expert Rev Mol Med       Date:  2010-01-18       Impact factor: 5.600

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