| Literature DB >> 1658103 |
T Kato1, T Shioiri, S Takahashi, T Inubushi.
Abstract
In vivo phosphorus-31 magnetic resonance spectroscopy (31P-MRS) was used to measure phosphorus metabolism in the brains of manic patients treated with lithium carbonate. The phosphomonoester (PME) peak was elevated in the manic state in patients with DSM-IIIR bipolar disorder compared to the euthymic state and to drug-free normal controls. Elevation of the PME peak may be caused by lithium-induced accumulation of inositol 1-phosphate in the brain.Entities:
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Year: 1991 PMID： 1658103 DOI： 10.1016/0165-0327(91)90064-y
Source DB: PubMed Journal: J Affect Disord ISSN： 0165-0327 Impact factor: 4.839