Literature DB >> 16580647

Immunohistochemical study on the distribution of TRPC channels in the rat hippocampus.

Yoon Hee Chung1, Hyang Sun Ahn, Daejin Kim, Dong Hoon Shin, Sung Su Kim, Kyung Yong Kim, Won Bok Lee, Choong Ik Cha.   

Abstract

In the present study, we performed immunohistochemistry using antibodies directed against TRPCs to study the localizations of these channels in rat hippocampus. The pyramidal cell bodies of CA1-3 areas and the granule cell bodies of the dentate gyrus were immunoreactive for TRPC1, TRPC3, TRPC4 and TRPC5. On the other hand, TRPC6 exhibited the cloud-like neuropil staining only in the molecular layer of the dentate gyrus. As a whole, the present study has clearly shown the localization of TRPCs in rat hippocampus and may provide useful data for the future investigations on the structural and functional properties of TRPCs.

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Year:  2006        PMID： 16580647     DOI： 10.1016/j.brainres.2006.02.087

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  26 in total

1.  Alternative splicing of the TRPC3 ion channel calmodulin/IP3 receptor-binding domain in the hindbrain enhances cation flux.

Authors:  Youngsoo Kim; Ann Chi Yan Wong; John M Power; Sherif F Tadros; Matthias Klugmann; Andrew J Moorhouse; Paul P Bertrand; Gary D Housley
Journal:  J Neurosci       Date:  2012-08-15       Impact factor: 6.167

2.  Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels.

Authors:  Jinbin Tian; Dhananjay P Thakur; Yungang Lu; Yingmin Zhu; Marc Freichel; Veit Flockerzi; Michael X Zhu
Journal:  Pflugers Arch       Date:  2014-07       Impact factor: 3.657

3.  Metabotropic glutamate receptors regulate hippocampal CA1 pyramidal neuron excitability via Ca²⁺ wave-dependent activation of SK and TRPC channels.

Authors:  Lynda El-Hassar; Anna M Hagenston; Lisa Bertetto D'Angelo; Mark F Yeckel
Journal:  J Physiol       Date:  2011-05-16       Impact factor: 5.182

Review 4.  TRPC Channels: Prominent Candidates of Underlying Mechanism in Neuropsychiatric Diseases.

Authors:  Chang Zeng; Fafa Tian; Bo Xiao
Journal:  Mol Neurobiol       Date:  2014-12-15       Impact factor: 5.590

Review 5.  TRPC Channels and Parkinson's Disease.

Authors:  Pramod Sukumaran; Yuyang Sun; Anne Schaar; Senthil Selvaraj; Brij B Singh
Journal:  Adv Exp Med Biol       Date:  2017       Impact factor: 2.622

6.  Development of a carbon-11 PET radiotracer for imaging TRPC5 in the brain.

Authors:  Yanbo Yu; Qianwa Liang; Hui Liu; Zonghua Luo; Hongzheng Hu; Joel S Perlmutter; Zhude Tu
Journal:  Org Biomol Chem       Date:  2019-06-05       Impact factor: 3.876

7.  Postsynaptic response to stimulation of the Schaffer collaterals with properties similar to those of synaptosomal aspartate release.

Authors:  Xuying Zhang; J Victor Nadler
Journal:  Brain Res       Date:  2009-08-05       Impact factor: 3.252

8.  Effects of a non-selective TRPC channel blocker, SKF-96365, on melittin-induced spontaneous persistent nociception and inflammatory pain hypersensitivity.

Authors:  Jing Ding; Jia-Rui Zhang; Yan Wang; Chun-Li Li; Dan Lu; Su-Min Guan; Jun Chen
Journal:  Neurosci Bull       Date:  2012-04       Impact factor: 5.203

9.  Transient receptor potential canonical 5 channels activate Ca2+/calmodulin kinase Igamma to promote axon formation in hippocampal neurons.

Authors:  Monika A Davare; Dale A Fortin; Takeo Saneyoshi; Sean Nygaard; Stefanie Kaech; Gary Banker; Thomas R Soderling; Gary A Wayman
Journal:  J Neurosci       Date:  2009-08-05       Impact factor: 6.167

10.  Upregulation and Diverse Roles of TRPC3 and TRPC6 in Synaptic Reorganization of the Mossy Fiber Pathway in Temporal Lobe Epilepsy.

Authors:  Chang Zeng; Pinting Zhou; Ting Jiang; Chunyun Yuan; Yan Ma; Li Feng; Renkai Liu; Weiting Tang; Xiaoyan Long; Bo Xiao; Fafa Tian
Journal:  Mol Neurobiol       Date:  2014-09-12       Impact factor: 5.590
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