Literature DB >> 16580256

Peroxisome proliferator-activated receptors and acute lung injury.

Salvatore Cuzzocrea1.   

Abstract

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors that are related to retinoid, steroid and thyroid hormone receptors. The PPAR subfamily comprises three members: PPAR-alpha, PPAR-beta and PPAR-gamma. PPARs have recently been implicated as regulators of cellular proliferation and inflammatory responses. Furthermore, it has been demonstrated that PPAR-gamma and PPAR-alpha reduce lung injury associated with inflammation and shock.

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Year:  2006        PMID： 16580256     DOI： 10.1016/j.coph.2006.01.008

Source DB:  PubMed          Journal:  Curr Opin Pharmacol        ISSN： 1471-4892            Impact factor:   5.547


  11 in total

1.  Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation.

Authors:  Rebecca L Charles; Joseph R Burgoyne; Manuel Mayr; Steven M Weldon; Norbert Hubner; Hua Dong; Christophe Morisseau; Bruce D Hammock; Aimee Landar; Philip Eaton
Journal:  Circ Res       Date:  2010-12-16       Impact factor: 17.367

2.  Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice.

Authors:  Hye-Youn Cho; Wesley Gladwell; Xuting Wang; Brian Chorley; Douglas Bell; Sekhar P Reddy; Steven R Kleeberger
Journal:  Am J Respir Crit Care Med       Date:  2010-03-11       Impact factor: 21.405

Review 3.  Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease.

Authors:  Maria G Belvisi; Jane A Mitchell
Journal:  Br J Pharmacol       Date:  2009-08-24       Impact factor: 8.739

Review 4.  Diabetes, insulin, and development of acute lung injury.

Authors:  Shyoko Honiden; Michelle N Gong
Journal:  Crit Care Med       Date:  2009-08       Impact factor: 7.598

5.  Development of telmisartan in the therapy of spinal cord injury: pre-clinical study in rats.

Authors:  Chien-Min Lin; Jo-Ting Tsai; Chen Kuei Chang; Juei-Tang Cheng; Jia-Wei Lin
Journal:  Drug Des Devel Ther       Date:  2015-08-14       Impact factor: 4.162

6.  Pulmonary phthalate exposure and asthma - is PPAR a plausible mechanistic link?

Authors:  Anette Kocbach Bølling; Jørn A Holme; Carl Gustaf Bornehag; Unni C Nygaard; Randi J Bertelsen; Eewa Nånberg; Johanna Bodin; Amrit Kaur Sakhi; Cathrine Thomsen; Rune Becher
Journal:  EXCLI J       Date:  2013-08-20       Impact factor: 4.068

7.  Caloric Restriction Is More Efficient than Physical Exercise to Protect from Cisplatin Nephrotoxicity via PPAR-Alpha Activation.

Authors:  Gabriel R Estrela; Frederick Wasinski; Rogério O Batista; Meire I Hiyane; Raphael J F Felizardo; Flavia Cunha; Danilo C de Almeida; Denise M A C Malheiros; Niels O S Câmara; Carlos C Barros; Michael Bader; Ronaldo C Araujo
Journal:  Front Physiol       Date:  2017-03-02       Impact factor: 4.566

8.  Rosiglitazone promotes ENaC-mediated alveolar fluid clearance in acute lung injury through the PPARγ/SGK1 signaling pathway.

Authors:  Jing He; Di Qi; Xu-Mao Tang; Wang Deng; Xin-Yu Deng; Yan Zhao; Dao-Xin Wang
Journal:  Cell Mol Biol Lett       Date:  2019-05-28       Impact factor: 5.787

9.  The Role of PPARs in Lung Fibrosis.

Authors:  Heather F Lakatos; Thomas H Thatcher; R Matthew Kottmann; Tatiana M Garcia; Richard P Phipps; Patricia J Sime
Journal:  PPAR Res       Date:  2007       Impact factor: 4.964

10.  Decrease of PPARδ in Type-1-Like Diabetic Rat for Higher Mortality after Spinal Cord Injury.

Authors:  Cheng-Chia Tsai; Kung-Shing Lee; Sheng-Hsien Chen; Li-Jen Chen; Keng-Fan Liu; Juei-Tang Cheng
Journal:  PPAR Res       Date:  2014-04-10       Impact factor: 4.964
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