Literature DB >> 16580153

A model linking biology, behavior and psychiatric diagnoses in perpetrators of domestic violence.

David T George1, Monte J Phillips, Linda Doty, John C Umhau, Robert R Rawlings.   

Abstract

Research indicates that perpetrators of domestic violence have abnormalities in central serotonin and testosterone metabolism, an increased sensitivity to anxiogenic stimuli, and an impaired neuro-connection between their cortex and the amygdala. Clinical evaluations show that perpetrators of domestic violence also have a distinguishing set of behaviors and diagnoses related to anxiety, depression, intermittent explosive disorder, and borderline personality disorder. In this paper we propose a model to understand how the biological abnormalities can potentially explain the behaviors and diagnoses exhibited by the perpetrators. Changes in the perpetrator's neurotransmitters lead to a heightened sensitivity to environmental stimuli, anxiety, and conditioned fear. Lack of cortical input to the amygdala impairs the perpetrator's ability to extinguish anxiety and/or conditioned fear and gives rise to either innate behaviors (e.g., fight, flight, and shut down) or learned fear avoidant behaviors designed to avoid anxiety (e.g., alcohol consumption, self-injurious acts, and obsessive behaviors). Linking conditioned fear and fear avoidance to the behaviors and psychiatric diagnoses will serve to change the way the medical community perceives and treats perpetrators of domestic violence.

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Year:  2006        PMID: 16580153     DOI: 10.1016/j.mehy.2006.01.049

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  6 in total

1.  Domestic violence: "What's love got to do with it?".

Authors:  Samir Al-Adawi; Sabah Al-Bahlani
Journal:  Sultan Qaboos Univ Med J       Date:  2007-04

2.  Fluoxetine treatment of alcoholic perpetrators of domestic violence: a 12-week, double-blind, randomized, placebo-controlled intervention study.

Authors:  David T George; Monte J Phillips; Mariel Lifshitz; Thomas A Lionetti; David E Spero; Niloofar Ghassemzedeh; Linda Doty; John C Umhau; Robert R Rawlings
Journal:  J Clin Psychiatry       Date:  2010-06-29       Impact factor: 4.384

3.  Biological Correlates of Intimate Partner Violence Perpetration.

Authors:  Lavinia A Pinto; Eric L Sullivan; Alan Rosenbaum; Nicole Wyngarden; John C Umhau; Mark W Miller; Casey T Taft
Journal:  Aggress Violent Behav       Date:  2010

4.  Are batterers different from other criminals? An fMRI study.

Authors:  Natalia Bueso-Izquierdo; Juan Verdejo-Román; Oren Contreras-Rodríguez; Martina Carmona-Perera; Miguel Pérez-García; Natalia Hidalgo-Ruzzante
Journal:  Soc Cogn Affect Neurosci       Date:  2016-02-16       Impact factor: 3.436

Review 5.  The physician's unique role in preventing violence: a neglected opportunity?

Authors:  John C Umhau; Karysse Trandem; Mohsin Shah; David T George
Journal:  BMC Med       Date:  2012-11-23       Impact factor: 8.775

6.  Evidence for biological roots in the transgenerational transmission of intimate partner violence.

Authors:  M I Cordero; G L Poirier; C Marquez; V Veenit; X Fontana; B Salehi; F Ansermet; C Sandi
Journal:  Transl Psychiatry       Date:  2012-04-24       Impact factor: 6.222

  6 in total

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