Literature DB >> 1657711

Class-3 porin protein of Neisseria meningitidis: cloning and structure of the gene.

S Butcher1, M Sarvas, K Runeberg-Nyman.   

Abstract

The gene coding for the class-3 protein of Neisseria meningitidis was cloned and sequenced. The deduced amino acid (aa) sequence was highly homologous (50-78%) to those of other neisserial porin proteins. Alignment of the aa sequence of five neisserial porin proteins pinpointed several regions of identity or near identity. These are assumed to be membrane-spanning beta-strands. A comparison of the homologies between these neisserial porins showed that the class-3 protein is most closely related to the Neisseria gonorrhoeae P1A protein.

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Year:  1991        PMID： 1657711     DOI： 10.1016/0378-1119(91)90523-e

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  13 in total

1.  Specificity of human bactericidal antibodies against PorA P1.7,16 induced with a hexavalent meningococcal outer membrane vesicle vaccine.

Authors:  E R van der Voort; P van der Ley; J van der Biezen; S George; O Tunnela; H van Dijken; B Kuipers; J Poolman
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

2.  Use of transformation to construct antigenic hybrids of the class 1 outer membrane protein in Neisseria meningitidis.

Authors:  P van der Ley; J van der Biezen; P Hohenstein; C Peeters; J T Poolman
Journal:  Infect Immun       Date:  1993-10       Impact factor: 3.441

3.  The physical map of the chromosome of a serogroup A strain of Neisseria meningitidis shows complex rearrangements relative to the chromosomes of the two mapped strains of the closely related species N. gonorrhoeae.

Authors:  J A Dempsey; A B Wallace; J G Cannon
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

4.  Correlation between serological and sequencing analyses of the PorB outer membrane protein in the Neisseria meningitidis serotyping system.

Authors:  C T Sacchi; A P Lemos; A M Whitney; C A Solari; M E Brandt; C E Melles; C E Frasch; L W Mayer
Journal:  Clin Diagn Lab Immunol       Date:  1998-05

Review 5.  Innate immune function of the neisserial porins and the relationship to vaccine adjuvant activity.

Authors:  Lee M Wetzler
Journal:  Future Microbiol       Date:  2010-05       Impact factor: 3.165

6.  Analysis of Neisseria meningitidis class 3 outer membrane protein gene variable regions and type identification using genetic techniques.

Authors:  M C Bash; K B Lesiak; S D Banks; C E Frasch
Journal:  Infect Immun       Date:  1995-04       Impact factor: 3.441

7.  Neisserial porins inhibit human neutrophil actin polymerization, degranulation, opsonin receptor expression, and phagocytosis but prime the neutrophils to increase their oxidative burst.

Authors:  R Bjerknes; H K Guttormsen; C O Solberg; L M Wetzler
Journal:  Infect Immun       Date:  1995-01       Impact factor: 3.441

8.  Proposed standardization of Neisseria meningitidis PorA variable-region typing nomenclature.

Authors:  C T Sacchi; A P Lemos; M E Brandt; A M Whitney; C E Melles; C A Solari; C E Frasch; L W Mayer
Journal:  Clin Diagn Lab Immunol       Date:  1998-11

9.  Identification of meningococcal serosubtypes by polymerase chain reaction.

Authors:  M C Maiden; J A Bygraves; J McCarvil; I M Feavers
Journal:  J Clin Microbiol       Date:  1992-11       Impact factor: 5.948

10.  Molecular analysis of the serotyping antigens of Neisseria meningitidis.

Authors:  I M Feavers; J Suker; A J McKenna; A B Heath; M C Maiden
Journal:  Infect Immun       Date:  1992-09       Impact factor: 3.441
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