Literature DB >> 16575720

Aerosolized ribavirin-induced reversible hepatotoxicity in a hematopoietic stem cell transplant recipient with Hodgkin lymphoma.

Jorge Chaves1, Auris Huen, Carlos Bueso-Ramos, Amar Safdar, Saroj Vadhan-Raj.   

Abstract

We describe a case of acute hepatic toxicity associated with aerosolized ribavirin in a bone marrow transplant recipient with documented respiratory syncytial virus infection. The temporal relationship with drug administration and the liver biopsy results suggested drug-induced hepatic injury. As the use of aerosolized ribavirin to treat respiratory syncytial virus infections continues, it is imperative that careful attention be paid to possible adverse effects of therapy in the high-risk population of immunosuppressed patients.

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Year:  2006        PMID: 16575720     DOI: 10.1086/502651

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  3 in total

1.  Clinical presentation and management of suspected ribavirin toxicosis in a dog.

Authors:  Kimberly Bridges; Nicole Beckel; Claire Sharp; Laura Stern
Journal:  Can Vet J       Date:  2016-05       Impact factor: 1.008

Review 2.  Respiratory syncytial virus in hematopoietic cell transplant recipients and patients with hematologic malignancies.

Authors:  Fareed Khawaja; Roy F Chemaly
Journal:  Haematologica       Date:  2019-06-20       Impact factor: 9.941

Review 3.  Drug-induced organ injury in coronavirus disease 2019 pharmacotherapy: Mechanisms and challenges in differential diagnosis and potential protective strategies.

Authors:  Mohammad Mehdi Ommati; Ali Mobasheri; Reza Heidari
Journal:  J Biochem Mol Toxicol       Date:  2021-05-11       Impact factor: 3.568

  3 in total

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