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Literature DB >> 16575459

Synthesis, stability and optimized photolytic cleavage of 4-methoxy-2-nitrobenzyl backbone-protected peptides.

Abstract

We demonstrate the potential of 4-methoxy-2-nitrobenzyl as a Boc chemistry-compatible fully reversible backbone modification for synthetic peptides.

Entities: Chemical

Mesh：

Substances：

Year: 2006 PMID： 16575459 DOI： 10.1039/b600304d

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

9 in total

1. Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit.

Authors: Sudarshan Rajagopal; Stephen B H Kent
Journal: Protein Sci Date: 2007-07-27 Impact factor: 6.725

2. Photochemically-activated probes of protein-protein interactions.

Authors: Sandip K Nandy; Richard S Agnes; David S Lawrence
Journal: Org Lett Date: 2007-05-17 Impact factor: 6.005

3. Controlling the Oligomerization State of Aβ-Derived Peptides with Light.

Authors: Patrick J Salveson; Sepehr Haerianardakani; Alexander Thuy-Boun; Adam G Kreutzer; James S Nowick
Journal: J Am Chem Soc Date: 2018-04-20 Impact factor: 15.419

4. A Caged Enkephalin Optimized for Simultaneously Probing Mu and Delta Opioid Receptors.

Authors: Matthew R Banghart; Xinyi J He; Bernardo L Sabatini
Journal: ACS Chem Neurosci Date: 2017-12-27 Impact factor: 4.418

Review 5. Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds.

Authors: Hsien-Ming Lee; Daniel R Larson; David S Lawrence
Journal: ACS Chem Biol Date: 2009-06-19 Impact factor: 5.100

Synthesis, stability and optimized photolytic cleavage of 4-methoxy-2-nitrobenzyl backbone-protected peptides.

1. Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit.

2. Photochemically-activated probes of protein-protein interactions.

3. Controlling the Oligomerization State of Aβ-Derived Peptides with Light.

4. A Caged Enkephalin Optimized for Simultaneously Probing Mu and Delta Opioid Receptors.

Review 5. Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds.

Review 6. Light-mediated remote control of signaling pathways.

7. Peptide backbone modification in the bend region of amyloid-β inhibits fibrillogenesis but not oligomer formation.

8. Automated synthesis of backbone protected peptides.

Review 9. Challenges and Perspectives in Chemical Synthesis of Highly Hydrophobic Peptides.