Maple T Landvoigt1, Charles J Mullett. 1. Department of Internal Medicine, West Virginia University School of Medicine, Morgantown, WV, USA.
Abstract
OBJECTIVE: To examine the efficacy of octreotide in resolving chylothoraces in infants and children following cardiac surgery. DESIGN: Retrospective chart review. SETTING: Pediatric intensive care unit of a tertiary care center. PATIENTS: All children who received octreotide for the treatment of chylothoraces following surgery for congenital heart disease over a 30-month period between 2001-2004. INTERVENTIONS: Octreotide infusion. MEASUREMENTS AND MAIN RESULTS: Eight courses of octreotide treatment were identified in seven patients who met our inclusion criteria. The median duration of therapy was 5 days, and dosing ranged from 1 to 4 microg/kg/hr. Treatment did not result in an overall decrease in average chest tube output after 3 days of therapy. However, in two patients (29%) the chylothoraces ultimately resolved during the octreotide infusion. Treatment was well tolerated, and no serious side effects were noted. CONCLUSION: In contrast to previously published reports, we find octreotide therapy for postoperative chylothoraces to be successful in only a minority of cases.
OBJECTIVE: To examine the efficacy of octreotide in resolving chylothoraces in infants and children following cardiac surgery. DESIGN: Retrospective chart review. SETTING: Pediatric intensive care unit of a tertiary care center. PATIENTS: All children who received octreotide for the treatment of chylothoraces following surgery for congenital heart disease over a 30-month period between 2001-2004. INTERVENTIONS:Octreotide infusion. MEASUREMENTS AND MAIN RESULTS: Eight courses of octreotide treatment were identified in seven patients who met our inclusion criteria. The median duration of therapy was 5 days, and dosing ranged from 1 to 4 microg/kg/hr. Treatment did not result in an overall decrease in average chest tube output after 3 days of therapy. However, in two patients (29%) the chylothoraces ultimately resolved during the octreotide infusion. Treatment was well tolerated, and no serious side effects were noted. CONCLUSION: In contrast to previously published reports, we find octreotide therapy for postoperative chylothoraces to be successful in only a minority of cases.
Authors: Nikoletta R Czobor; György Roth; Zsolt Prodán; Daniel J Lex; Erzsébet Sápi; László Ablonczy; Mihály Gergely; Edgar A Székely; János Gál; Andrea Székely Journal: J Thorac Dis Date: 2017-08 Impact factor: 2.895
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