| Literature DB >> 16575173 |
M Fukasawa1, S Morita, M Kimura, T Horii, T Ochiya, I Hatada.
Abstract
To address the function of RNA interference (RNAi) in transcriptional silencing in mammals, we analyzed genomic imprinting in Dicer1-hypomorphic mice, in which Dicer1 expression was significantly reduced. We did not observe any abnormality in the allelic expression of imprinted genes in these mice or their offspring, suggesting that reduced expression of Dicer1 did not significantly affect the maintenance and reprogramming of imprinting. 2006 S. Karger AG, Basel.Entities:
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Year: 2006 PMID： 16575173 DOI： 10.1159/000090825
Source DB: PubMed Journal: Cytogenet Genome Res ISSN： 1424-8581 Impact factor: 1.636