PURPOSE: To assess red blood cell transfusion practices among Canadian anesthesiologists. METHODS: A survey depicting three realistic clinical scenarios of elective surgical procedures with different risks of bleeding was administered to all Canadian practicing members (n = 2,100) of the Canadian Anesthesiologists' Society. Respondents were requested to choose hemoglobin thresholds for which they would transfuse red blood cells under various conditions within each scenario. RESULTS: We obtained a response rate of 47% (719/1,512). Transfusion thresholds differed significantly between baseline scenarios. A threshold above 70 g x L(-1) was chosen by 48% of respondents in the general surgery scenario compared to 56% in the orthopedic surgery scenario and 79% in the vascular surgery scenario (P < 0.001). A history of coronary artery disease was associated with a transfusion threshold >or= 100 g x L(-1) in a significant proportion of respondents ranging from 20% in the orthopedic surgery scenario to 31% in the general surgery scenario and to 49% in the vascular surgery scenario (P < 0.001). Conversely, changing the patient's age from 60 to 20 yr resulted in the adoption of a transfusion threshold <or= 60 g x L(-1) by > 30% of respondents in two scenarios (P < 0.001). The year of respondent graduation was strongly associated with these findings. CONCLUSION: There was significant variation in transfusion practices among Canadian anesthesiologists. The type of surgical procedure, patient's age and a history of coronary artery disease influenced reported transfusion threshold. Practice variation in specific subgroups would support the need for further research to identify optimal transfusion thresholds.
PURPOSE: To assess red blood cell transfusion practices among Canadian anesthesiologists. METHODS: A survey depicting three realistic clinical scenarios of elective surgical procedures with different risks of bleeding was administered to all Canadian practicing members (n = 2,100) of the Canadian Anesthesiologists' Society. Respondents were requested to choose hemoglobin thresholds for which they would transfuse red blood cells under various conditions within each scenario. RESULTS: We obtained a response rate of 47% (719/1,512). Transfusion thresholds differed significantly between baseline scenarios. A threshold above 70 g x L(-1) was chosen by 48% of respondents in the general surgery scenario compared to 56% in the orthopedic surgery scenario and 79% in the vascular surgery scenario (P < 0.001). A history of coronary artery disease was associated with a transfusion threshold >or= 100 g x L(-1) in a significant proportion of respondents ranging from 20% in the orthopedic surgery scenario to 31% in the general surgery scenario and to 49% in the vascular surgery scenario (P < 0.001). Conversely, changing the patient's age from 60 to 20 yr resulted in the adoption of a transfusion threshold <or= 60 g x L(-1) by > 30% of respondents in two scenarios (P < 0.001). The year of respondent graduation was strongly associated with these findings. CONCLUSION: There was significant variation in transfusion practices among Canadian anesthesiologists. The type of surgical procedure, patient's age and a history of coronary artery disease influenced reported transfusion threshold. Practice variation in specific subgroups would support the need for further research to identify optimal transfusion thresholds.
Authors: David J Murphy; David Howard; Angela Muriithi; Pedro Mendez-Tellez; Jonathan Sevransky; Carl Shanholtz; Giora Netzer; Peter J Pronovost; Dale M Needham Journal: Crit Care Med Date: 2009-06 Impact factor: 7.598