Literature DB >> 16574600

EXpression of ErbB proteins in human prostate.

K Nasu1, N Tanji, R Nishioka, J Wang, Y Yanagihara, A Ozawa, M Yokoyama, K Sakayama.   

Abstract

ErbB proteins are widely expressed in human and animal tissues, notably in cells of epithelial or neuroendocrine origin. Protein expression and interactions of ErbBs were examined in prostate cancer specimens. Expression of ErbB1-4 proteins was determined with immunohistochemical methods using each monoclonal antibody in 20 prostatic adenocarcinomas. The 4 ErbB proteins were widely expressed in normal, hyperplastic and cancerous tissues of the prostate. ErbBs may contribute to normal development or tumor growth and progression in human prostate.

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Year:  2006        PMID： 16574600     DOI： 10.1080/01485010500316238

Source DB:  PubMed          Journal:  Arch Androl        ISSN： 0148-5016


  3 in total

Review 1.  Functions of normal and malignant prostatic stem/progenitor cells in tissue regeneration and cancer progression and novel targeting therapies.

Authors:  Murielle Mimeault; Parmender P Mehta; Ralph Hauke; Surinder K Batra
Journal:  Endocr Rev       Date:  2008-02-21       Impact factor: 19.871

2.  MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer.

Authors:  Wenqing Qi; Larry S Cooke; Amy Stejskal; Christopher Riley; Kimiko Della Croce; Jose W Saldanha; David Bearss; Daruka Mahadevan
Journal:  BMC Cancer       Date:  2009-05-11       Impact factor: 4.430

3.  A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study.

Authors:  Joanne M Murabito; Carol L Rosenberg; Daniel Finger; Bernard E Kreger; Daniel Levy; Greta Lee Splansky; Karen Antman; Shih-Jen Hwang
Journal:  BMC Med Genet       Date:  2007-09-19       Impact factor: 2.103
  3 in total

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