Literature DB >> 16574528

QT interval prolongation associated with venlafaxine administration.

Konstantinos Letsas, Panagiotis Korantzopoulos, Loucas Pappas, Dimitrios Evangelou, Michalis Efremidis, Fotis Kardaras.   

Abstract

A significant number of non-antiarrhythmic drugs including psychotropic agents have been shown to prolong cardiac repolarization increasing the risk for torsade de pointes ventricular tachycardia. We briefly describe a 60-year-old woman who admitted to the hospital due to hypertension and mild dyspnea having a prolonged QT interval (QTc: 582 ms). The patient had a known history of depression treated with venlafaxine. The QT interval normalised a few days after cessation of the antidepressant agent. This is the first report of venlafaxine-induced QT interval prolongation.

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Year:  2006        PMID: 16574528     DOI: 10.1016/j.ijcard.2005.03.065

Source DB:  PubMed          Journal:  Int J Cardiol        ISSN: 0167-5273            Impact factor:   4.164


  20 in total

Review 1.  The QT interval and psychotropic medications in children: recommendations for clinicians.

Authors:  Paul McNally; Fiona McNicholas; Paul Oslizlok
Journal:  Eur Child Adolesc Psychiatry       Date:  2006-08-29       Impact factor: 4.785

Review 2.  Evaluating the risk of QTc prolongation associated with antidepressant use in older adults: a review of the evidence.

Authors:  Matthew P Rochester; Allison M Kane; Sunny Anne Linnebur; Danielle R Fixen
Journal:  Ther Adv Drug Saf       Date:  2018-05-04

Review 3.  Impact of Age and Sex on QT Prolongation in Patients Receiving Psychotropics.

Authors:  Simon W Rabkin
Journal:  Can J Psychiatry       Date:  2015-05       Impact factor: 4.356

Review 4.  QTc prolongation by psychotropic drugs and the risk of Torsade de Pointes.

Authors:  Katharina Wenzel-Seifert; Markus Wittmann; Ekkehard Haen
Journal:  Dtsch Arztebl Int       Date:  2011-10-14       Impact factor: 5.594

5.  Selective serotonin reuptake inhibitors and torsade de pointes: new concepts and new directions derived from a systematic review of case reports.

Authors:  Christopher Kogut; Ericka Breden Crouse; W Victor R Vieweg; Mehrul Hasnain; Adrian Baranchuk; Geneviève C Digby; Jayanthi N Koneru; Antony Fernandez; Anand Deshmukh; Jules C Hancox; Ananda K Pandurangi
Journal:  Ther Adv Drug Saf       Date:  2013-10

6.  Evaluation of a QT nomogram for risk assessment after antidepressant overdose.

Authors:  W Stephen Waring; Ann Graham; Julie Gray; Allen D Wilson; Catherine Howell; D Nicholas Bateman
Journal:  Br J Clin Pharmacol       Date:  2010-12       Impact factor: 4.335

Review 7.  Cardiovascular toxicity due to venlafaxine poisoning in adults: a review of 235 consecutive cases.

Authors:  C Howell; A D Wilson; W S Waring
Journal:  Br J Clin Pharmacol       Date:  2007-02-12       Impact factor: 4.335

Review 8.  Proarrhythmic risk with antipsychotic and antidepressant drugs: implications in the elderly.

Authors:  W Victor R Vieweg; Mark A Wood; Antony Fernandez; Mary Beatty-Brooks; Mehrul Hasnain; Anand K Pandurangi
Journal:  Drugs Aging       Date:  2009       Impact factor: 3.923

Review 9.  QTc interval prolongation and torsade de pointes associated with second-generation antipsychotics and antidepressants: a comprehensive review.

Authors:  Mehrul Hasnain; W Victor R Vieweg
Journal:  CNS Drugs       Date:  2014-10       Impact factor: 5.749

10.  A review of the suitability of duloxetine and venlafaxine for use in patients with depression in primary care with a focus on cardiovascular safety, suicide and mortality due to antidepressant overdose.

Authors:  David Taylor; Alan Lenox-Smith; Andrew Bradley
Journal:  Ther Adv Psychopharmacol       Date:  2013-06
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